DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and chw-1

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_505686.1	Gene:	chw-1 / 184848	WormBaseID:	WBGene00009059	Length:	207	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	63/234 - (26%)
Similarity:	106/234 - (45%)	Gaps:	45/234 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKMDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVL 65
            |.|.::|    :.:||:.||:.|||||.:|.:...|.:.      ..:|||  |.|.:.:.
Worm     1 MAKEEDE----KCLKCIFVGNAAVGKTSMIVSYTTNVYP------HNYVPT--AFDNFSVV---- 49

  Fly    66 ERSWEVVDGVNVSLRLWDTFGDHDKD--RRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRF 128
                .:||...:.|:|.||.|....|  |...|..:||.::.:|:....|..:....||||:.:.
Worm    50 ----VLVDKKPIRLQLHDTAGQSSFDTLRPLCYTDADVFVIVYSVVDLQSFEDVSHHWYPEVTKR 110

  Fly   129 CPDVPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSV 193
            .|...:||||.:.|.|:..|        |...|.:|            .:|:|..||..::|.|.
Worm   111 NPGTKLILVGTQADQRWQVR--------GNTVTQLR------------GKALADRLGAEFFECSA 155

  Fly   194 FTYFGVNEVFENAIRSALIAR--RQQRF-WMTNLKKVQK 229
            .|...:.::|:.||.:.|..:  |::|. :.|...|:::
Worm   156 LTQHNLKQMFDAAILAGLEGKKNREKRSNFYTKSSKIKE 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	55/199 (28%)
		RHO	16..211	CDD:197554	54/196 (28%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
chw-1	NP_505686.1	Wrch_1	10..172	CDD:133330	55/197 (28%)
chw-1	NP_505686.1	RHO	12..174	CDD:197554	54/197 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900