DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and mig-2

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_509931.1	Gene:	mig-2 / 181344	WormBaseID:	WBGene00003239	Length:	195	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	78/207 - (37%)
Similarity:	108/207 - (52%)	Gaps:	28/207 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78
            :|||:|||..||||.::.:      .:.......:||||:  |.|.....        :||..|:
Worm     8 IKCVVVGDGTVGKTCMLIS------YTTDSFPVQYVPTVF--DNYSAQMS--------LDGNVVN 56

  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141
            |.||||.|  |:|:.|..:|.::||.:||||:.||:|..|....|.||||:.|||.||||||.|.
Worm    57 LGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKL 121

  Fly   142 DLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFTYFGVNEVFENA 206
            ||    |||      .|....::|..||.:......:...|...|.|.|.|..|..|:.:|||:|
Worm   122 DL----RDE------AEPMRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDA 176

  Fly   207 IRSALIARRQQR 218
            :||.|..:.|::
Worm   177 VRSILHPKPQKK 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	75/197 (38%)
		RHO	16..211	CDD:197554	75/196 (38%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
mig-2	NP_509931.1	Rho	8..178	CDD:206641	74/195 (38%)
mig-2	NP_509931.1	RHO	10..183	CDD:197554	76/198 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810