DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rho-1

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_502959.1	Gene:	rho-1 / 178458	WormBaseID:	WBGene00004357	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	83/207 - (40%)
Similarity:	114/207 - (55%)	Gaps:	30/207 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSL 79
            |.|:|||.|.|||.|:..      .|..|....:||||     :..|...:|     |||..|.|
Worm     7 KLVIVGDGACGKTCLLIV------FSKDQFPDVYVPTV-----FENYVADIE-----VDGKQVEL 55

  Fly    80 RLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKND 142
            .||||.|  |:|:.|..:|..:||:|:||||.||.||.|....|.||:|.|||:||:||||.|.|
Worm    56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRD 120

  Fly   143 LRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVFENA 206
            ||...:....|           |.:|.:.|.|::.||:|:::|. ||.|.|..|..|:.||||.|
Worm   121 LRSDPQTVREL-----------AKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKA 174

  Fly   207 IRSALIARRQQR 218
            .::||..:::::
Worm   175 TQAALQQKKKKK 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	81/197 (41%)
		RHO	16..211	CDD:197554	80/197 (41%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rho-1	NP_502959.1	RhoA_like	5..179	CDD:206662	81/198 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810