DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoBTB and cdc-42

DIOPT Version :9

Sequence 1:NP_001262107.1 Gene:RhoBTB / 40249 FlyBaseID:FBgn0036980 Length:783 Species:Drosophila melanogaster
Sequence 2:NP_495598.1 Gene:cdc-42 / 174233 WormBaseID:WBGene00000390 Length:191 Species:Caenorhabditis elegans


Alignment Length:210 Identity:74/210 - (35%)
Similarity:105/210 - (50%) Gaps:30/210 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN 76
            :.:|||:|||.|||||.|:.:...||      ..|.:||||:  |.|.:        ..::.|..
 Worm     2 QTIKCVVVGDGAVGKTCLLISYTTNK------FPSEYVPTVF--DNYAV--------TVMIGGEP 50

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            .:|.|:||.|  |:|:.|..:|.::||.|:|||:.:|.|..|.:..|.|||...|...|.:|||.
 Worm    51 YTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGT 115

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKEL-GVAYYETSVFTYFGVNEVF 203
            :.|||   .|...|....:.        |...|..|....:|||| .|.|.|.|..|..|:..||
 Worm   116 QVDLR---DDPGMLEKLAKN--------KQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVF 169

  Fly   204 ENAIRSALIARRQQR 218
            :.||.:||...:|::
 Worm   170 DEAILAALDPPQQEK 184

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoBTBNP_001262107.1 RhoBTB 12..210 CDD:133275 71/200 (36%)
RHO 16..211 CDD:197554 70/197 (36%)
BTB <392..446 CDD:295341
BTB 481..575 CDD:279045
BTB 485..582 CDD:197585
cdc-42NP_495598.1 Cdc42 3..177 CDD:206664 71/200 (36%)
RHO 6..179 CDD:197554 72/199 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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