DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RhoBTB and RHOV

DIOPT Version :9

Sequence 1:NP_001262107.1 Gene:RhoBTB / 40249 FlyBaseID:FBgn0036980 Length:783 Species:Drosophila melanogaster
Sequence 2:NP_598378.3 Gene:RHOV / 171177 HGNCID:18313 Length:236 Species:Homo sapiens


Alignment Length:232 Identity:82/232 - (35%)
Similarity:115/232 - (49%) Gaps:34/232 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PKMDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLE 66
            |......|.:..:|||||||.||||:.||.:..||.:.      :.:.||  |:|.:.:  .|| 
Human    20 PPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYP------ARYRPT--ALDTFSV--QVL- 73

  Fly    67 RSWEVVDGVNVSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFC 129
                 |||..|.:.||||.|  |.|:.|...|..:||.|.|||:..|.|.:|....|.||||...
Human    74 -----VDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHN 133

  Fly   130 PDVPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKEL-GVAYYETSV 193
            |..||:|||.:.|||   .|.|.|....:.|       :...|...:|:.:|::: ...|.|.|.
Human   134 PQAPVLLVGTQADLR---DDVNVLIQLDQGG-------REGPVPQPQAQGLAEKIRACCYLECSA 188

  Fly   194 FTYFGVNEVFENAIRSAL--IARRQQRFWMTNLKKVQ 228
            .|...:.|||::||.||:  .||.:::.   |.|.|:
Human   189 LTQKNLKEVFDSAILSAIEHKARLEKKL---NAKGVR 222

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoBTBNP_001262107.1 RhoBTB 12..210 CDD:133275 73/200 (37%)
RHO 16..211 CDD:197554 73/197 (37%)
BTB <392..446 CDD:295341
BTB 481..575 CDD:279045
BTB 485..582 CDD:197585
RHOVNP_598378.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..27 1/6 (17%)
Wrch_1 32..205 CDD:133330 73/198 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.