DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and Rhoc

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001278788.1	Gene:	Rhoc / 11853	MGIID:	106028	Length:	193	Species:	Mus musculus

Alignment Length:	207	Identity:	83/207 - (40%)
Similarity:	108/207 - (52%)	Gaps:	30/207 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSL 79
            |.|:|||.|.|||.|:..      .|..|....:||||     :..|...:|     |||..|.|
Mouse     7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTV-----FENYIADIE-----VDGKQVEL 55

  Fly    80 RLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKND 142
            .||||.|  |:|:.|..:|..:||:|:||||.||.||.|....|.||::.|||:||:||||.|.|
Mouse    56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

  Fly   143 LRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVFENA 206
            ||   :||:.....        |.:|.:.|..:|.|.:|..:.. .|.|.|..|..||.||||.|
Mouse   121 LR---QDEHTRREL--------AKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMA 174

  Fly   207 IRSALIARRQQR 218
            .|:.|..|:.:|
Mouse   175 TRAGLQVRKNKR 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	80/197 (41%)
		RHO	16..211	CDD:197554	79/197 (40%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Rhoc	NP_001278788.1	RhoA_like	5..179	CDD:206662	80/198 (40%)
Rhoc	NP_001278788.1	Effector region. /evidence=ECO:0000255	34..42		4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900