DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhov

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001122131.1	Gene:	rhov / 100038217	XenbaseID:	XB-GENE-489435	Length:	240	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	84/231 - (36%)
Similarity:	121/231 - (52%)	Gaps:	34/231 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NEQPH-QEL-VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERS 68
            |.:|: ||| :|||||||.|||||.|:.:...|.:.:..|      ||  |:|.:.:  .||
Frog    27 NSRPNSQELGIKCVLVGDGAVGKTSLVISYTINGYPTEYQ------PT--ALDTFSV--QVL--- 78

  Fly    69 WEVVDGVNVSLRLWDTFGDHDKD--RRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPD 131
               |||..|.::|.||.|..|.|  |...|..:||.|:|||:.:|.|.:|....|.||||...|.
Frog    79 ---VDGAPVRIQLCDTAGQEDFDHLRSLCYAETDVFLVCFSVVNPSSFQNVTEKWIPEIRTHSPH 140

  Fly   132 VPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKEL-GVAYYETSVFT 195
            .|::|||.:.|||   .|.|.|.      ...|:.:|.  |...:|:|||::: ...|.|.|..|
Frog   141 TPIVLVGTQADLR---DDVNVLI------NLSRSHVKP--VSESQAQAVAQKIRAQTYIECSALT 194

  Fly   196 YFGVNEVFENAIRSAL--IARRQQRFWMTNLKKVQK 229
            ...:.|||:.:|.||:  .||.:::.....:|::.|
Frog   195 QKNLKEVFDASILSAIKHKARLEKKLTSKGVKRLSK 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	75/201 (37%)
		RHO	16..211	CDD:197554	73/197 (37%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhov	NP_001122131.1	Wrch_1	37..209	CDD:133330	73/198 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910