DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ide and AT2G41790

DIOPT Version :9

Sequence 1:	NP_524182.3	Gene:	Ide / 40248	FlyBaseID:	FBgn0001247	Length:	990	Species:	Drosophila melanogaster
Sequence 2:	NP_181710.1	Gene:	AT2G41790 / 818778	AraportID:	AT2G41790	Length:	970	Species:	Arabidopsis thaliana

Alignment Length:	952	Identity:	358/952 - (37%)
Similarity:	536/952 - (56%)	Gaps:	13/952 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGT 91
            |.|...|.|:||.:.|:|.|:|||||||:||..||::||.||..|||..|.|||||.|||||..:
plant    15 ILKPRTDNREYRMIVLKNLLQVLLISDPDTDKCAASMSVSVGSFSDPQGLEGLAHFLEHMLFYAS 79

  Fly    92 EKYPHENGYTTYLSQSGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREI 156
            ||||.|:.|:.|:::.|||:||.|....|.|||.|..|..|.||||||||||.||.:..||.|||
plant    80 EKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNADCFDEALDRFAQFFIKPLMSADATMREI 144

  Fly   157 NAVNSEHEKNLPSDLWRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQW 221
            .||:||::|||.||.|||:|:.:||:|.||.|.||.:||..||...|::|.:|.|.||:||:::.
plant   145 KAVDSENQKNLLSDGWRIRQLQKHLSKEDHPYHKFSTGNMDTLHVRPQAKGVDTRSELIKFYEEH 209

  Fly   222 YSANIMCLAVIGKESLDELEGMVLEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIRSL 286
            ||||||.|.|.||||||:::.:|...|.||:|.|..||.:|..|...:.....||.:|||....|
plant   210 YSANIMHLVVYGKESLDKIQDLVERMFQEIQNTNKVVPRFPGQPCTADHLQILVKAIPIKQGHKL 274

  Fly   287 TISFTTDDLTQFYKSGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGFGFFDIVVD 351
            .:|:........|...|..||.|||||||:||:...|:.|||...|.||.......:.||.:.:|
plant   275 GVSWPVTPSIHHYDEAPSQYLGHLIGHEGEGSLFHALKTLGWATGLSAGEGEWTLDYSFFKVSID 339

  Fly   352 LTQEGLEHVDDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQI 416
            ||..|.||:.:|:.::|.|:::|::.|..:|||||...:.|.:|.:::|..|.:.:....|:|||
plant   340 LTDAGHEHMQEILGLLFNYIQLLQQTGVCQWIFDELSAICETKFHYQDKIPPMSYIVDIASNMQI 404

  Fly   417 FPLEEVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAKD 481
            :|.::.|:...|..::.|.:::.::|||.||..||...||.||...|.|||:|.|.|.:.::...
plant   405 YPTKDWLVGSSLPTKFNPAIVQKVVDELSPSNFRIFWESQKFEGQTDKAEPWYNTAYSLEKITSS 469

  Fly   482 TVQSWENCELNENLKLALPNSFIPTNFDISDVPADAPKHPTIILDTPILRVWHKQDNQFNKPKAC 546
            |:|.|.....:.:|.|..||.||||:..:.|.. |....|.::..||..|:|:|.|..|:||||.
plant   470 TIQEWVQSAPDVHLHLPAPNVFIPTDLSLKDAD-DKETVPVLLRKTPFSRLWYKPDTMFSKPKAY 533

  Fly   547 MTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTIRGFSDKQ 611
            :..|.:.|:|...|....|..:...||.|.||||.|.|::|.|...|.....|.:.|:.|::.|.
plant   534 VKMDFNCPLAVSSPDAAVLTDIFTRLLMDYLNEYAYYAQVAGLYYGVSLSDNGFELTLLGYNHKL 598

  Fly   612 VVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLALLLTENAWANMELLDA 676
            .:|||.::..:.:|.:...||.::||...:..:|:|..|||..::||.:|:|.:..|...|.||.
plant   599 RILLETVVGKIANFEVKPDRFAVIKETVTKEYQNYKFRQPYHQAMYYCSLILQDQTWPWTEELDV 663

  Fly   677 MELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRVNTRLEATNASK---LPILARQML 738
            :..:..:.|..|......|...||:|.|||...:|..:...:...|  .|..|   .|:...|.|
plant   664 LSHLEAEDVAKFVPMLLSRTFIECYIAGNVENNEAESMVKHIEDVL--FNDPKPICRPLFPSQHL 726

  Fly   739 KKREYKLLAGDSYLFEKE--NEFHKSSCAQLYLQCGAQTDHTNIMVNLVSQVLSEPCYDCLRTKE 801
            ..|..||..|..|.:.::  |...::|....|:|........||.:.|...|..:..:..|||.|
plant   727 TNRVVKLGEGMKYFYHQDGSNPSDENSALVHYIQVHRDDFSMNIKLQLFGLVAKQATFHQLRTVE 791

  Fly   802 QLGYIVFSGVRKVNGANGIRIIVQSA-KHPSYVEDRIENFLQTYLQVIEDMPLDEFERHKEALAV 865
            |||||.....|..:|..|::.|:||: |.|.:::.|:|:.|:.:...:.:|..::|:.:..||..
plant   792 QLGYITALAQRNDSGIYGVQFIIQSSVKGPGHIDSRVESLLKNFESKLYEMSNEDFKSNVTALID 856

  Fly   866 KKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVAILRKISKADFVDYFKKFIAKDGEERRVLSV 930
            .||||.|.:.::...::.||...|..|.|:||||:.|:::.|.:.:|:|.::|......::.||:
plant   857 MKLEKHKNLKEESRFYWREIQSGTLKFNRKEAEVSALKQLQKQELIDFFDEYIKVGAARKKSLSI 921

  Fly   931 HIVSQQTDENATSEAEPVEITNMERHKPISDIVTFKSCKELY 972
            .:...|..:...|:.:.|...::|    |.|||.|:..:.|:
plant   922 RVYGSQHLKEMASDKDEVPSPSVE----IEDIVGFRKSQPLH 959

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ide	NP_524182.3	Ptr	25..952	CDD:223956	351/930 (38%)
		Peptidase_M16	47..185	CDD:279066	82/137 (60%)
		Peptidase_M16_C	211..386	CDD:282978	72/174 (41%)
		Peptidase_M16_M	395..676	CDD:292805	95/280 (34%)
		Peptidase_M16_C	680..863	CDD:282978	51/188 (27%)
AT2G41790	NP_181710.1	Ptr	15..944	CDD:223956	351/931 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	190	1.000	Domainoid score	I946
eggNOG	1	0.900	-	-		E1_COG1025
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3645
Inparanoid	1	1.050	652	1.000	Inparanoid score	I166
OMA	1	1.010	-	-		QHG63000
OrthoDB	1	1.010	-	-		D1008844at2759
OrthoFinder	1	1.000	-	-		FOG0000548
OrthoInspector	1	1.000	-	-		otm2487
orthoMCL	1	0.900	-	-		OOG6_100422
Panther	1	1.100	-	-	LDO	PTHR43690
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1417
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840