Protein Alignment Ide and Nrd1

DIOPT Version :9

• Sequence 1: NP_524182.3
• Gene: Ide / 40248
• FlyBaseID: FBgn0001247
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: NP_572757.2
• Gene: Nrd1 / 32143
• FlyBaseID: FBgn0030344
• Length: 1147
• Species: Drosophila melanogaster
• Alignment Length: 1111
• Identity: 286/1111 - (25%)
• Similarity: 488/1111 - (43%)
• Gaps: 206/1111 - (18%)

  Fly    28 EKSLQDTRDYRGLQLENGLKVLLISDP------------------------------------NT 56
            :||..|.:.|:.|.|.|||..|::|||                                    :|
  Fly    54 DKSETDKKLYKTLLLGNGLHALIVSDPSPMPHDGFTTSESSSSKSTVSTSSSIISRSESTSSTST 118

  Fly    57 D---------------VSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQ 106
            |               ::|.||.:..|..::||...|||||.|||:|:|:||||.||.:..::.:
  Fly   119 DSESSEESSSEEGDEKLAACALLIDYGSFAEPTKYQGLAHFLEHMIFMGSEKYPKENIFDAHIKK 183

  Fly   107 SGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDL 171
            .||.:||.|....|.::|.||...||.:||.|.....|||....|.:||.:||:||.::.|..|.
  Fly   184 CGGFANANTDCEDTLFYFEVAEKHLDSSLDYFTALMKAPLMKQEAMQRERSAVDSEFQQILQDDE 248

  Fly   172 WRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNID---VRDELLKFHKQWYSANIMCLAVIG 233
            .|..|:...||.....:..|..||..:|.|     |:|   :...|.:..|:.|.||.|.:.:..
  Fly   249 TRRDQLLASLATKGFPHGTFAWGNMKSLKE-----NVDDAELHKILHEIRKEHYGANRMYVCLQA 308

  Fly   234 KESLDELEGMVLEKFSEIENKNVKVPGWPRHPYAE----ERYGQKVKIVPIKDIRSLTISFTTDD 294
            :..:||||.:|:..||.|.:..||.|......|.:    |.:.|...:.|:::...|.:::...:
  Fly   309 RLPIDELESLVVRHFSGIPHNEVKAPDLSSFNYKDAFKAEFHEQVFFVKPVENETKLELTWVLPN 373

  Fly   295 LTQFYKSGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGF------GFFDIVVDLT 353
            :.|:|:|.||.:|::|:|:||:||:.:.|||..|...|:||..  :|||      ..|:|.:.||
  Fly   374 VRQYYRSKPDQFLSYLLGYEGRGSLCAYLRRRLWALQLIAGID--ENGFDMNSMYSLFNICIYLT 436

  Fly   354 QEGLEHVDDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQIFP 418
            .||.:::|:::...|.|:::....|..|.:::|..:..|..|||..:....:.|...|.:::.||
  Fly   437 DEGFKNLDEVLAATFAYVKLFANCGSMKDVYEEQQRNEETGFRFHAQRPAFDNVQELVLNLKYFP 501

  Fly   419 LEEVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDC---DLAEPYYKTKYGITRVAK 480
            .:::|....|..|:..:.:|.|:..|...|..:::.|:....|.   |..|.::.|:|....:.:
  Fly   502 PKDILTGKELYYEYNEEHLKELISHLNEMKFNLMVTSRRKYDDISAYDKTEEWFGTEYATIPMPE 566

  Fly   481 DTVQSWENCELNENLKLALPNSFIPTNFDI---SDVPADAPKHPTIILDTPILRVWHKQDNQFNK 542
            ...:.||:......|.|...|.::..:|.:   |....:.|..|.:::.|....:|.:||::|:.
  Fly   567 KWRKLWEDSVPLPELFLPESNKYVTDDFTLHWHSMGRPEVPDSPKLLIKTDTCELWFRQDDKFDL 631

  Fly   543 PKACMTFDMSNPIAYLDPLN---CNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTI 604
            |:|.|.|...:|:...:..|   |:|...||   :..:.|.||.|..|.|..|:.....|:...:
  Fly   632 PEAHMAFYFISPMQRQNAKNDAMCSLYEEMV---RFHVCEELYPAISAGLSYSLSTIEKGLLLKV 693

  Fly   605 RGFSDKQVVLLEKLLDHLFDF--SIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLALL----- 662
            .|:::|..:::|.:.:.:.:.  ::||......       :||       |...::.||:
  Fly   694 CGYNEKLHLIVEAIAEGMLNVAETLDENMLSAF-------VKN-------QRKAFFNALIKPKAL 744

  Fly   663 --------LTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRVN 719
                    |....|..:.....:..|..:.:..||.:|.:.|:.:..|.||.|::.|.::   :|
  Fly   745 NRDIRLCVLERIRWLMINKYKCLSSVILEDMREFAHQFPKELYIQSLIQGNYTEESAHNV---MN 806

  Fly   720 TRLEATNASKLPILARQMLKKREYKLLAGDSYLFEKENEFHKSSCAQL-----------YLQCGA 773
            :.|...|..::....| .|:....||..|.|.:          .|..|           :.|.|.
  Fly   807 SLLSRLNCKQIRERGR-FLEDITVKLPVGTSII----------RCHALNVQDTNTVITNFYQIGP 860

  Fly   774 QTDHTNIMVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQSAKHPS---YVED 835
            .|.....:::|:...:.||.:|.|||||||||.|.:.||...|..|..|:|.|.:..:   |||.
  Fly   861 NTVRVESILDLLMMFVDEPLFDQLRTKEQLGYHVGATVRLNYGIAGYSIMVNSQETKTTADYVEG 925

  Fly   836 RIENFLQTYLQVIEDMPLDEFERHKEALAVKKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVA 900
            |||.|....||::..:|.||:|..:::|...||.....:..:.|:.:.||..::|.|:|...::.
  Fly   926 RIEVFRAKMLQILRHLPQDEYEHTRDSLIKLKLVADLALSTEMSRNWDEIINESYLFDRRRRQIE 990

  Fly   901 ILRKISKADFVDYFKKFIAKDGEERRVLSVHIV-------------------------------- 933
            :||.:.|.:.:::   .|:.||:..|.|||.::
  Fly   991 VLRTLQKDEIINF---VISIDGDNMRKLSVQVIGHRPAGMPEPLCGEDTAKCASKSDDESESEND 1052

  Fly   934 ---SQQTDENATSEAEPVEITNMERHKP----------------------------ISDIVTFKS 967
               .:..:|..:||.|..|....|..|.                            |:||..||.
  Fly  1053 DDDDEDEEEEESSEEEEEEEKEKEGLKGEDEDDLFYSLENKLNIVFLPAKFNNAFIITDIEKFKD 1117

  Fly   968 CKELYP 973
            .:.:||
  Fly  1118 DQYVYP 1123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ide	NP_524182.3	Ptr	25..952	CDD:223956	277/1060 (26%)
		Peptidase_M16	47..185	CDD:279066	58/188 (31%)
		Peptidase_M16_C	211..386	CDD:282978	55/184 (30%)
		Peptidase_M16_M	395..676	CDD:292805	64/304 (21%)
		Peptidase_M16_C	680..863	CDD:282978	58/196 (30%)
Nrd1	NP_572757.2	Ptr	54..1023	CDD:223956	272/1009 (27%)
		Peptidase_M16	136..246	CDD:279066	47/109 (43%)
		Peptidase_M16_C	289..472	CDD:282978	56/184 (30%)
		Peptidase_M16_M	478..766	CDD:292805	64/304 (21%)
		Peptidase_M16_C	769..953	CDD:282978	58/197 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445074
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1025
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1008844at2759
OrthoFinder	1	1.000	-	-		FOG0000548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100422
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R767
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.680