Protein Alignment Ide and Nrdc

DIOPT Version :10

• Sequence 1: NP_524182.3
• Gene: Ide / 40248
• FlyBaseID: FBgn0001247
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: NP_001334098.1
• Gene: Nrdc / 230598
• MGIID: 1201386
• Length: 1229
• Species: Mus musculus
• Alignment Length: 953
• Identity: 317/953 - (33%)
• Similarity: 511/953 - (53%)
• Gaps: 45/953 - (4%)

  Fly    53 DPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYP 117
            :.:|.:|||||.|.||..:||.:|||||||.|||:|:|:.|||.|||:..:|.:.|||.||:|..
Mouse   284 ETDTVLSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDC 348

  Fly   118 LMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDLWRIKQVNRHLA 182
            ..|.:.|.|.......||||:|||||.||....|.:||:.||:||::...|||..|.:.:...||
Mouse   349 ERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLA 413

  Fly   183 KPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVIGKESLDELEGMVLEK 247
            :|.|...||..||..||...||..|||....|.:|..::|||:.|.|.|..||:||.||..|.|.
Mouse   414 RPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEI 478

  Fly   248 FSEIENKNVKVPGWPR--HPYAEERYGQKVKIVPIKDIRSLTISFTTDDLTQFYKSGPDNYLTHL 310
            ||:|.|..:..|.:..  .|:....:.:..::|||:.|.:|||::......|.|:..|.:|::.|
Mouse   479 FSQIPNNGLPKPNFSHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWL 543

  Fly   311 IGHEGKGSILSELRRLGWCNDLMAGHQNT---QNG-FGFFDIVVDLTQEGLEHVDDIVKIVFQYL 371
            :||||||||||.||:..|...|..|:..|   ||. :..|.|.:.||.||.||..::...|||||
Mouse   544 VGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYL 608

  Fly   372 EMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQIFPLEEVLIAPYLSNEWRPDL 436
            :||:|.||:|.:|:|..|:.:..|.::|:..|...|.:...:||::|.::.|....|..|::|::
Mouse   609 KMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEV 673

  Fly   437 IKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAKDTVQSWE-NCELNENLKLALP 500
            |...|::|||.|:.:|::|.:.|..|||.|.::.|:|.|..:.....:.|: |.:||.:|.|...
Mouse   674 IAEALNQLVPQKANLVLLSGANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNPDLHLPAE 738

  Fly   501 NSFIPTNFDISDVPADAPKHPTIILDTPILRVWHKQDNQFNKPKACMTFDMSNPIAYLDPLNCNL 565
            |.:|.|:|.:........::|..|::|....:|:|:||:|..|||.:.|.:.:|:......|..|
Mouse   739 NKYIATDFTLKAFDCPETEYPAKIVNTAQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVL 803

  Fly   566 NHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTIRGFSDKQVVLLEKLLDHLFDFSIDEK 630
            ..:.|.:|...|.|..|:|::|.|:..::....|:...::||:.|..:|.:.::|:|.:||....
Mouse   804 FDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSSTPA 868

  Fly   631 RFDILKEEYVRSLKNFKAEQPYQHSIYYLALLLTENAWANME----LLDAMELVTYDRVLNFAKE 691
            .|.::.|:..::..|... :|...:.....|:|..:.|:.::    |:|.:.|   |.:|||.|:
Mouse   869 VFTMITEQLKKTYFNILI-KPETLAKDVRLLILEYSRWSMIDKYQALMDGLSL---DSLLNFVKD 929

  Fly   692 FFQRLHTECFIFGNVTKQQATDIAGRVNTRLEATNASKLPILARQMLKKREYKLLAGDSYLFEKE 756
            |..:|..|..:.||||..::.|....|..:|      ....|.|:|..:.:...|....:|.:..
Mouse   930 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKL------NFAPLEREMPVQFQVVELPSGHHLCKVR 988

  Fly   757 --NEFHKSSCAQLYLQCGAQTDHTNIMVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANG 819
              |:...:|...:|.|.|.::.....::.|:...:.|||:|.||||:.|||.|:...|..:|..|
Mouse   989 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILG 1053

  Fly   820 IRIIV--QSAKHPS-YVEDRIENFLQTYLQVIEDMPLDEFERHKEALAVKKLEKPKTIFQQFSQF 881
            ..:.|  |:.|:.| .|:.:||.||.::.:.||::..|.|.....||...|..:...:.::..:.
Mouse  1054 FSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRN 1118

  Fly   882 YGEIAMQTYHFEREEAEVAILRKISKADFVDYFKKFIAKDGEERRVLSVHIV---SQQTDENA-- 941
            :.|:..|.|.|:|...|:..|:..||:|.|.:||   |..|...::||||:|   ..:.:|:.
Mouse  1119 WNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFK---AHRGPGSKMLSVHVVGYGKYELEEDGAP 1180

  Fly   942 ----TSEAEPVEITNM-------ERHKPISDIVTFKSCKELYP 973
                ::..|.:::|.:       |...||:||..|.:...|:|
Mouse  1181 FGEDSNSREGMQLTYLPPSPVLAESTTPITDIRAFTATLSLFP 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ide	NP_524182.3	Ptr	25..954	CDD:440648	309/932 (33%)
Nrdc	NP_001334098.1	Ptr	286..1223	CDD:440648	316/949 (33%)