Protein Alignment Ide and F44E7.4

DIOPT Version :10

• Sequence 1: NP_524182.3
• Gene: Ide / 40248
• FlyBaseID: FBgn0001247
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: NP_741543.1
• Gene: F44E7.4 / 178966
• WormBaseID: WBGene00018426
• Length: 1067
• Species: Caenorhabditis elegans
• Alignment Length: 985
• Identity: 396/985 - (40%)
• Similarity: 588/985 - (59%)
• Gaps: 32/985 - (3%)

  Fly    27 IEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGT 91
            |.|..||.|:||||:|.||::|||:|||.||.|||||.|:|||:.||..||||||||||||||||
 Worm    75 IVKGAQDAREYRGLELTNGIRVLLVSDPTTDKSAAALDVKVGHLMDPWELPGLAHFCEHMLFLGT 139

  Fly    92 EKYPHENGYTTYLSQSGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREI 156
            .|||.||.|:.:|:...|||||.|....|.|||.|.||:|.||||||.|||::|.||.||||||:
 Worm   140 AKYPSENEYSKFLAAHAGSSNAYTSSDHTNYHFDVKPDQLPGALDRFVQFFLSPQFTESATEREV 204

  Fly   157 NAVNSEHEKNLPSDLWRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQW 221
            .||:|||..||.:||||..||:|..:||.|.|.|||:|||.||.|..:.|.|:.||.||:|||:|
 Worm   205 CAVDSEHSNNLNNDLWRFLQVDRSRSKPGHDYGKFGTGNKQTLLEDARKKGIEPRDALLQFHKKW 269

  Fly   222 YSANIMCLAVIGKESLDELEGMV--LEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIR 284
            ||::||...::|||.|:.||..:  || |..||||.|:...|...||..::..:::.:|||||.|
 Worm   270 YSSDIMTCCIVGKEPLNVLESYLGTLE-FDAIENKKVERKVWEEFPYGPDQLAKRIDVVPIKDTR 333

  Fly   285 SLTISFTTDDLTQFYKSGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGFGFFDIV 349
            .::|||...||...:.|.|.:|::|||||||.||:||||:||||.:.|.:.......|||.:::.
 Worm   334 LVSISFPFPDLNGEFLSQPGHYISHLIGHEGPGSLLSELKRLGWVSSLQSDSHTQAAGFGVYNVT 398

  Fly   350 VDLTQEGLEHVDDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSM 414
            :||:.|||||||:|::::|.|:.||:..|||:|:.||..:|:.::||||:||||..:..:..:|:
 Worm   399 MDLSTEGLEHVDEIIQLMFNYIGMLQSAGPKQWVHDELAELSAVKFRFKDKEQPMTMAINVAASL 463

  Fly   415 QIFPLEEVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFE-PDCDLAEPYYKTKYGITRV 478
            |..|.|.:|.:.||..::.|:.||.||..|.|:..::.:|||.|: .:.:..||.|.|:..:|.:
 Worm   464 QYIPFEHILSSRYLLTKYEPERIKELLSMLSPANMQVRVVSQKFKGQEGNTNEPVYGTEMKVTDI 528

  Fly   479 AKDTVQSWENCELNENLKLALP--NSFIPTNFDISDVPADAPK--HPTIILDTPILRVWHKQDNQ 539
            :.:|::.:||.....:..|.||  |.:|.||||  ..|.::.|  ||.:|.|....|||.|||::
 Worm   529 SPETMKKYENALKTSHHALHLPEKNEYIATNFD--QKPRESVKNEHPRLISDDGWSRVWFKQDDE 591

  Fly   540 FNKPKACMTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTI 604
            :|.||......::.|:...:|....|:.:.:..|.|.|.|..|:|:||.||..:.....|:...:
 Worm   592 YNMPKQETKLALTTPMVAQNPRMSLLSSLWLWCLSDTLAEETYNADLAGLKCQLESSPFGVQMRV 656

  Fly   605 R----------------GFSDKQVVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQ 653
            .                |:.:||.:..:.|.:.:.:|.||:.|||:|.|...|:|.|....|||.
 Worm   657 SNRREAERHASLTLHVYGYDEKQALFAKHLANRMTNFKIDKTRFDVLFESLKRALTNHAFSQPYL 721

  Fly   654 HSIYYLALLLTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRV 718
            .:.:|..||:.:..|:..:||...:.||.:.|..||||..|..|.|.|:.||.|:::|..::..:
 Worm   722 LTQHYNQLLIVDKVWSKEQLLAVCDSVTLEDVQGFAKEMLQAFHMELFVHGNSTEKEAIQLSKEL 786

  Fly   719 NTRLEATNASKLPILARQMLKKREYKLLAGDSYLFEKENEFHKSSCAQLYLQCGAQTDHTNIMVN 783
            ...|::...:..|:...:...:||.:|..||.|::....:.|...|.::..|.|.|..:.|.:|.
 Worm   787 MDVLKSAAPNSRPLYRNEHNPRRELQLNNGDEYVYRHLQKTHDVGCVEVTYQIGVQNTYDNAVVG 851

  Fly   784 LVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQSAKHPSYVEDRIENFLQTYLQVI 848
            |:.|::.||.::.|||.|.|||||::|.|...|...:.:|||..|...:|.:|||.||::..:.|
 Worm   852 LIDQLIREPAFNTLRTNEALGYIVWTGSRLNCGTVALNVIVQGPKSVDHVLERIEVFLESVRKEI 916

  Fly   849 EDMPLDEFERHKEALAVKKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVAILRKISKADFVDY 913
            .:||.:||:.....:..:..|||||:..:|.:|:.||..:.|:|.|.|.|||:|:.|.|.|.::.
 Worm   917 AEMPQEEFDNQVSGMIARLEEKPKTLSSRFRRFWNEIECRQYNFARREEEVALLKTIKKDDVLEL 981

  Fly   914 FKKFIAKDGEERRVLSVHIVSQQTDENATSEAEPVEITNMERHKPISDIVTFKSCKELYPI---A 975
            |.|.|.||..|||.|:|.:..:..|:.|.:   .:...|.|..|...:::.....::..|:   .
 Worm   982 FDKKIRKDAAERRKLAVFVHGKNEDQEAVN---TIIKKNAESGKKEKEVLYSDQLRQFLPLYGRP 1043

  Fly   976 LPFLDIKAKG 985
            :..:|:|..|
 Worm  1044 IAAIDLKPIG 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ide	NP_524182.3	Ptr	25..954	CDD:440648	390/949 (41%)
F44E7.4	NP_741543.1	Ptr	75..1010	CDD:440648	388/937 (41%)