DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Toll-9 and GSO1

DIOPT Version :9

Sequence 1:	NP_001246846.1	Gene:	Toll-9 / 40245	FlyBaseID:	FBgn0036978	Length:	900	Species:	Drosophila melanogaster
Sequence 2:	NP_193747.2	Gene:	GSO1 / 827760	AraportID:	AT4G20140	Length:	1249	Species:	Arabidopsis thaliana

Alignment Length:	734	Identity:	162/734 - (22%)
Similarity:	268/734 - (36%)	Gaps:	179/734 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PKYIWDVIVLVCLFLGN-------VREAYTEFSIQDGLIIEPDSATTSSEEAEEVSKERTDLKSL 60
            |:..|::..|:.|.|.|       .:...:..:..:.|::  .....|.|...|:||.:: ||.|
plant   304 PEEFWNMSQLLDLVLANNHLSGSLPKSICSNNTNLEQLVL--SGTQLSGEIPVELSKCQS-LKQL 365

  Fly    61 MLKYESDDGN--SCLLDLIK--DEVIWWQFPNGTLRDSTKKYAHKLYLDLSHGNLKDDSDLFREA 121
            .|...|..|:  ..|.:|::  |..:......|||..|.....:..:|.|.|.||        |.
plant   366 DLSNNSLAGSIPEALFELVELTDLYLHNNTLEGTLSPSISNLTNLQWLVLYHNNL--------EG 422

  Fly   122 KLSRKVTIWR-TEVFSAAFNTLTAAPFRTLYSMR------------ESLKLLSLRGNNFAELIPD 173
            ||.::::..| .||.             .||..|            .|||::.:.||:|...||.
plant   423 KLPKEISALRKLEVL-------------FLYENRFSGEIPQEIGNCTSLKMIDMFGNHFEGEIPP 474

  Fly   174 AEDFARFVNESRL---EASNSVP---HHCELLLLHNTTDLYDR----------------ECYLYF 216
            :....:.:|...|   |....:|   .:|..|   |..||.|.                |..:.:
plant   475 SIGRLKELNLLHLRQNELVGGLPASLGNCHQL---NILDLADNQLSGSIPSSFGFLKGLEQLMLY 536

  Fly   217 NNNT--NMGQSITTGRNYTNFIKVLKDRFDQ--H---GSSSQSIAWATFPKMPRLVELDISNCSI 274
            ||:.  |:..|:.:.||.|. |.:..:|.:.  |   ||||             .:..|::|...
plant   537 NNSLQGNLPDSLISLRNLTR-INLSHNRLNGTIHPLCGSSS-------------YLSFDVTNNGF 587

  Fly   275 EYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLSFTNFLTYSYQLQL-------- 331
            |........|..||.||.:..|::......|...::.:..||:| :|.||.:..|||
plant   588 EDEIPLELGNSQNLDRLRLGKNQLTGKIPWTLGKIRELSLLDMS-SNALTGTIPLQLVLCKKLTH 651

  Fly   332 ------------PTLEMALSLIYGLKIQQNVF-KYLP-------ELIYLDLSHSKMTRNSAVAFA 376
                        |.....||.:..||:..|.| :.||       :|:.|.|..:.:..:......
plant   652 IDLNNNFLSGPIPPWLGKLSQLGELKLSSNQFVESLPTELFNCTKLLVLSLDGNSLNGSIPQEIG 716

  Fly   377 HLG-------DKLKFLSLCYTAIPMVSSTIFKNTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKY 434
            :||       ||.:|..    ::|.....:.|   |..|.||.|                :....
plant   717 NLGALNVLNLDKNQFSG----SLPQAMGKLSK---LYELRLSRN----------------SLTGE 758

  Fly   435 LYFERSNIKDLEWSKSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNN 499
            :..|...::||:        ..|.|:.||.....|:...:|..||.||||.|.:......:..:.
plant   759 IPVEIGQLQDLQ--------SALDLSYNNFTGDIPSTIGTLSKLETLDLSHNQLTGEVPGSVGDM 815

  Fly   500 SALRVLNLRSNTINMLSNEMLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLN 564
            .:|..||:   :.|.|..::.|.|.|....|...|..:|...|.....| .:|||....|.|.:.
plant   816 KSLGYLNV---SFNNLGGKLKKQFSRWPADSFLGNTGLCGSPLSRCNRV-RSNNKQQGLSARSVV 876

  Fly   565 Y-----SQNAVGEEVISLAESLIIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSS----- 619
            .     :..|:|..::.:|  |...::....:.:.....:|::....::|.|....|..:
plant   877 IISAISALTAIGLMILVIA--LFFKQRHDFFKKVGHGSTAYTSSSSSSQATHKPLFRNGASKSDI 939

  Fly   620 --EDYMVAKCSAAQPYHLG 636
              ||.|.|..:.::.:.:|
plant   940 RWEDIMEATHNLSEEFMIG 958

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_001246846.1	leucine-rich repeat	157..185	CDD:275380	8/27 (30%)
		LRR_8	262..322	CDD:290566	13/59 (22%)
		leucine-rich repeat	264..287	CDD:275380	4/22 (18%)
		leucine-rich repeat	288..311	CDD:275380	5/22 (23%)
		leucine-rich repeat	312..356	CDD:275380	18/71 (25%)
		LRR_8	<344..387	CDD:290566	14/57 (25%)
		leucine-rich repeat	357..381	CDD:275380	5/30 (17%)
		leucine-rich repeat	382..397	CDD:275380	2/14 (14%)
		leucine-rich repeat	405..430	CDD:275380	5/24 (21%)
		LRR_8	431..488	CDD:290566	16/56 (29%)
		leucine-rich repeat	432..453	CDD:275380	3/20 (15%)
		LRR_RI	<449..536	CDD:238064	23/86 (27%)
		leucine-rich repeat	454..477	CDD:275380	6/22 (27%)
		LRR_8	477..536	CDD:290566	17/58 (29%)
		leucine-rich repeat	478..501	CDD:275380	7/22 (32%)
		leucine-rich repeat	502..525	CDD:275380	7/22 (32%)
		TIR	751..891	CDD:214587
GSO1	NP_193747.2	LRRNT_2	23..66	CDD:285463
		PLN00113	25..1235	CDD:215061	162/734 (22%)
		leucine-rich repeat	73..96	CDD:275380
		leucine-rich repeat	97..120	CDD:275380
		leucine-rich repeat	121..144	CDD:275380
		leucine-rich repeat	145..168	CDD:275380
		leucine-rich repeat	169..192	CDD:275380
		leucine-rich repeat	193..240	CDD:275380
		leucine-rich repeat	217..237	CDD:275380
		LRR_RI	238..442	CDD:238064	38/161 (24%)
		leucine-rich repeat	241..264	CDD:275380
		leucine-rich repeat	265..288	CDD:275380
		LRR_8	288..348	CDD:290566	7/45 (16%)
		leucine-rich repeat	289..312	CDD:275380	2/7 (29%)
		leucine-rich repeat	313..337	CDD:275380	4/23 (17%)
		leucine-rich repeat	338..361	CDD:275380	6/24 (25%)
		leucine-rich repeat	362..385	CDD:275380	8/22 (36%)
		leucine-rich repeat	386..409	CDD:275380	5/22 (23%)
		leucine-rich repeat	410..433	CDD:275380	8/30 (27%)
		leucine-rich repeat	434..457	CDD:275380	5/35 (14%)
		leucine-rich repeat	458..481	CDD:275380	7/22 (32%)
		leucine-rich repeat	482..505	CDD:275380	5/22 (23%)
		leucine-rich repeat	506..527	CDD:275380	5/23 (22%)
		leucine-rich repeat	530..553	CDD:275380	5/22 (23%)
		leucine-rich repeat	601..624	CDD:275380	5/22 (23%)
		leucine-rich repeat	625..648	CDD:275380	9/23 (39%)
		LRR_RI	649..843	CDD:238064	48/227 (21%)
		leucine-rich repeat	649..672	CDD:275380	2/22 (9%)
		leucine-rich repeat	673..696	CDD:275380	6/22 (27%)
		leucine-rich repeat	697..720	CDD:275380	4/22 (18%)
		leucine-rich repeat	721..744	CDD:275380	4/26 (15%)
		leucine-rich repeat	745..768	CDD:275380	6/38 (16%)
		leucine-rich repeat	769..793	CDD:275380	7/31 (23%)
		leucine-rich repeat	818..838	CDD:275380	7/22 (32%)
		PKc_like	957..1230	CDD:304357	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000