DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Toll-9 and AT4G11340

DIOPT Version :9

Sequence 1:	NP_001246846.1	Gene:	Toll-9 / 40245	FlyBaseID:	FBgn0036978	Length:	900	Species:	Drosophila melanogaster
Sequence 2:	NP_192873.1	Gene:	AT4G11340 / 826736	AraportID:	AT4G11340	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	77/382 - (20%)
Similarity:	138/382 - (36%)	Gaps:	98/382 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 CSYRLLNYSQNAVGEEVISL--AESLIIDRKLWQSR-----------YIPW----LQRSYSNIRE 605
            |:..||....| .|..:.:|  |...:|..|..:||           |.||    |:.::..:
plant    50 CTIILLTIDAN-FGPMIANLRRARFRVILVKSIRSRAFKLEPDSRNPYPPWDFEGLEHNFYEM-- 111

  Fly   606 FNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLDGDLTLKFQLLDYEASQYYCFNNTDQLQ---- 666
            |...:.:|...||.  ||:.: .|.:...|.|.|.|..:...:..|...    .:.|:.::
plant   112 FATISQLIPFEFSL--YMIHQ-HAVESIFLNDADDDEWVMIIITHYHLD----LDKTEMIECKAV 169

  Fly   667 --VDELNCQ----IRSMSDLAEELHHVTNTVIAVMGSLVGACILGFIIYLKRWHIHYYYSSLKSA 725
              :.:|.|.    |||.|:.|.|:|        :|..||.|.              ::..||
plant   170 AAIRDLICPRLGIIRSSSEGAVEIH--------IMVLLVEAA--------------WFLESL--- 209

  Fly   726 ALLSSASKESVNKFTNISQRDPSAVYDIFISYCQNDRTWVLNELLPNVEETGDVSICLHERDFQI 790
                      ..|...:..|.|.. :.:|:|:..:|..:.....|.:......:::...| |...
plant   210 ----------TEKVLAVKGRAPPQ-HQVFVSFRGSDVRYNFFSFLKDALIKNGINVVTDE-DAPR 262

  Fly   791 GVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFEMYLAQHRI-----------FEVSKEHLILV 844
            |..|.:|::..:..|...::|.|..:..|.||..|:...:.::           |||...|:.|
plant   263 GKPIDENLLKLIKDSRIAVVIFSENYPESTWCLDELVEIEKQMDLKMLDSCPIFFEVETCHVKL- 326

  Fly   845 FLEDIPRRKRPKTLQYLMDVKTYIKWPTAKEDRKLFWKRLKRSLE-----VIGINSR 896
               .:.|    .|..|.:....:.:...|::..|..|:..::..|     :|.:.||
plant   327 ---QVAR----STFNYNLLQLEHDERKKARQISKKAWEDAEKRFEGWRKALISVASR 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_001246846.1	leucine-rich repeat	157..185	CDD:275380
		LRR_8	262..322	CDD:290566
		leucine-rich repeat	264..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..356	CDD:275380
		LRR_8	<344..387	CDD:290566
		leucine-rich repeat	357..381	CDD:275380
		leucine-rich repeat	382..397	CDD:275380
		leucine-rich repeat	405..430	CDD:275380
		LRR_8	431..488	CDD:290566
		leucine-rich repeat	432..453	CDD:275380
		LRR_RI	<449..536	CDD:238064
		leucine-rich repeat	454..477	CDD:275380
		LRR_8	477..536	CDD:290566
		leucine-rich repeat	478..501	CDD:275380
		leucine-rich repeat	502..525	CDD:275380
		TIR	751..891	CDD:214587	28/155 (18%)
AT4G11340	NP_192873.1	TIR	224..402	CDD:279864	31/162 (19%)
AT4G11340	NP_192873.1	TIR	414..>470	CDD:279864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010