DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Toll-9 and AT3G04220

DIOPT Version :9

Sequence 1:	NP_001246846.1	Gene:	Toll-9 / 40245	FlyBaseID:	FBgn0036978	Length:	900	Species:	Drosophila melanogaster
Sequence 2:	NP_001326120.1	Gene:	AT3G04220 / 819577	AraportID:	AT3G04220	Length:	896	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	103/482 - (21%)
Similarity:	176/482 - (36%)	Gaps:	134/482 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LYLDLSHGNLKDDSDLFREAKLSRKVTIWRTEVFSAAFNTLTAAPFRTLYSM--------RESLK 158
            |:|.|:.....||::|. |.:|.:|.:..|..:...|..:|.....| |..|        ||.::
plant   487 LFLHLACSFHNDDTELV-EQQLGKKFSDLRQGLHVLAEKSLIHMDLR-LIRMHVLLAQLGREIVR 549

  Fly   159 LLSLRGNNFAELIPDAEDFARFVNESRLEASNSVPHHCELLLLHNTTDLYDRECYLYFNNNT--- 220
            ..|:......:.:.||.|....:.:.  ..|.||                   ..:.|:.||
plant   550 KQSIHEPGQRQFLVDATDIREVLTDD--TGSRSV-------------------IGIDFDFNTMEK 593

  Fly   221 --NMGQSITTGRNYTNFIKVLKDRFDQHG-----------------------------SSSQSIA 254
              ::.:....|.:...||::..|.|.:||                             ...:.:.
plant   594 ELDISEKAFRGMSNLQFIRIYGDLFSRHGVYYFGGRGHRVSLDYDSKLHFPRGLDYLPGKLRLLH 658

  Fly   255 WATFP--KMPR------LVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQG 311
            |..||  .:|.      ||:|.:....:|    :.:..:..||.|
plant   659 WQQFPMTSLPSEFHAEFLVKLCMPYSKLE----KLWEGIQPLRNL-------------------- 699

  Fly   312 VQYLDLSFTNFLTYSYQLQLPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFA 376
             ::|||:.:..|.     :||.|..|.:|      |:...:....|:.|..|..:.|
plant   700 -EWLDLTCSRNLK-----ELPDLSTATNL------QRLSIERCSSLVKLPSSIGEAT-------- 744

  Fly   377 HLGDKLKFLSL--CYTAIPMVSSTIFKN-TVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFE 438
                .||.::|  |.:.:.:.||  |.| |.|:.|||  ....|...:..:|..:||.....::|
plant   745 ----NLKKINLRECLSLVELPSS--FGNLTNLQELDL--RECSSLVELPTSFGNLANVESLEFYE 801

  Fly   439 RSNIKDLEWS-KSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSAL 502
            .|::..|..: .:|.||:||||...:.....|:.|.:|.:|::|:|..........|:|.|.:.|
plant   802 CSSLVKLPSTFGNLTNLRVLGLRECSSMVELPSSFGNLTNLQVLNLRKCSTLVELPSSFVNLTNL 866

  Fly   503 RVLNLRSNTINMLSNEMLKDFERLDYL 529
            ..|:||.     .|:.:...|..:.||
plant   867 ENLDLRD-----CSSLLPSSFGNVTYL 888

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_001246846.1	leucine-rich repeat	157..185	CDD:275380	4/27 (15%)
		LRR_8	262..322	CDD:290566	11/65 (17%)
		leucine-rich repeat	264..287	CDD:275380	4/22 (18%)
		leucine-rich repeat	288..311	CDD:275380	3/22 (14%)
		leucine-rich repeat	312..356	CDD:275380	10/43 (23%)
		LRR_8	<344..387	CDD:290566	7/42 (17%)
		leucine-rich repeat	357..381	CDD:275380	4/23 (17%)
		leucine-rich repeat	382..397	CDD:275380	4/16 (25%)
		leucine-rich repeat	405..430	CDD:275380	6/24 (25%)
		LRR_8	431..488	CDD:290566	16/57 (28%)
		leucine-rich repeat	432..453	CDD:275380	4/21 (19%)
		LRR_RI	<449..536	CDD:238064	24/81 (30%)
		leucine-rich repeat	454..477	CDD:275380	8/22 (36%)
		LRR_8	477..536	CDD:290566	14/53 (26%)
		leucine-rich repeat	478..501	CDD:275380	6/22 (27%)
		leucine-rich repeat	502..525	CDD:275380	6/22 (27%)
		TIR	751..891	CDD:214587
AT3G04220	NP_001326120.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010