DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-9 and kek6

DIOPT Version :9

Sequence 1:NP_001246846.1 Gene:Toll-9 / 40245 FlyBaseID:FBgn0036978 Length:900 Species:Drosophila melanogaster
Sequence 2:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster


Alignment Length:540 Identity:96/540 - (17%)
Similarity:168/540 - (31%) Gaps:229/540 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   264 LVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTF--------YYVQGVQYLDLSFT 320
            |..:.:....::|:.||:|||:..|..:.:||||:..:..|||        .|:.|.....|:  
  Fly    97 LQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLA-- 159

  Fly   321 NFLTYSYQLQLPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFAHLGDKLKFL 385
                 :||                      |..||.|..||:....::....::.|:| :.|:||
  Fly   160 -----AYQ----------------------FPILPHLRTLDMHDCLISYIDPMSLANL-NLLEFL 196

  Fly   386 SLCYTAIPMVSSTIFKNTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLE---- 446
            :|             ||.:||.|.                       :|::...:|:|.|.    
  Fly   197 NL-------------KNNLLESLS-----------------------EYVFQHMAN
LKTLSLEEN 225

  Fly   447 -WSKSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNL--- 507
             |..:.|..:..|                                ||     .||.|..::|   
  Fly   226 PWQCNCKLRKFRG--------------------------------WY-----VNSRLSSVSLVCK 253

  Fly   508 -----RSNTINMLSNEM--------LKDFERLDYLSLGDN-DFICDCHLRAVVEVA-AANNKDAD 557
                 :..|.:.:.:|:        :.:.|.:..:.:|.| .|.|..:...:.||| ..|.|..|
  Fly   254 GPPAQKDRTWDSVDDELFGCPPRVEIFNNEEVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILD 318

  Fly   558 CSYRLLNYSQNAVGEEVISLAESLIIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDY 622
                         .:.|:..:||:..| |||            ||:..||               
  Fly   319 -------------NDNVLFESESIASD-KLW------------SNLTVFN--------------- 342

  Fly   623 MVAKCSAAQPYHLGDLDGDLTLKFQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSD-----LAE 682
                                     :...:|..|.|..:.          .|.||:.     |:|
  Fly   343 -------------------------VTSLDAGTYACTGSN----------SIGSMTQNISIYLSE 372

  Fly   683 ELHHVT----------NTVIAVMGSLVGACILGFIIYL----KRWHIHYYYSSLKSAALLSSASK 733
            .:.||.          ..::.:.|::.....:.|::.|    .|.|.|...:.:||:...:...|
  Fly   373 IVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFVVCLCKRTTRQHRHANKAGVKSSVSFNDQEK 437

  Fly   734 ESVNKFTNISQRDPSAVYDI 753
            :.::.....:..|....|.|
  Fly   438 KLLDSSVTTTTNDRGDSYGI 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-9NP_001246846.1 leucine-rich repeat 157..185 CDD:275380
LRR_8 262..322 CDD:290566 18/65 (28%)
leucine-rich repeat 264..287 CDD:275380 7/22 (32%)
leucine-rich repeat 288..311 CDD:275380 9/30 (30%)
leucine-rich repeat 312..356 CDD:275380 5/43 (12%)
LRR_8 <344..387 CDD:290566 11/42 (26%)
leucine-rich repeat 357..381 CDD:275380 5/23 (22%)
leucine-rich repeat 382..397 CDD:275380 4/14 (29%)
leucine-rich repeat 405..430 CDD:275380 3/24 (13%)
LRR_8 431..488 CDD:290566 7/61 (11%)
leucine-rich repeat 432..453 CDD:275380 5/25 (20%)
LRR_RI <449..536 CDD:238064 13/103 (13%)
leucine-rich repeat 454..477 CDD:275380 1/22 (5%)
LRR_8 477..536 CDD:290566 11/75 (15%)
leucine-rich repeat 478..501 CDD:275380 3/22 (14%)
leucine-rich repeat 502..525 CDD:275380 4/38 (11%)
TIR 751..891 CDD:214587 2/3 (67%)
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380
LRR_8 96..155 CDD:290566 17/57 (30%)
leucine-rich repeat 97..120 CDD:275380 7/22 (32%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR_4 144..186 CDD:289563 11/70 (16%)
leucine-rich repeat 145..168 CDD:275380 7/51 (14%)
leucine-rich repeat 169..216 CDD:275380 15/83 (18%)
LRRCT 225..274 CDD:214507 11/85 (13%)
Ig 295..367 CDD:143165 25/147 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453675
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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