Protein Alignment Toll-9 and CG4950

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 617
• Identity: 130/617 - (21%)
• Similarity: 231/617 - (37%)
• Gaps: 145/617 - (23%)

  Fly   188 ASNSVPHHCELLLLHNTTDLYDRECYLYFNNN--TNMGQSITTGRNYT-------NFIKVLKDRF 243
            :...:|..|         |.||...|:..|..  |..|.::|..:|..       |.:|.:|
  Fly    24 SGGDIPLRC---------DEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMK--- 76

  Fly   244 DQHGSSSQSIAWATFPKMPRLVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYY 308
             .:.|:...:.:..|...|.|..||:||.:|..:::.||...|||..|.::.|.:.:|....|..
  Fly    77 -FYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIG 140

  Fly   309 VQGVQYLDLSFTNFLTYSYQL-----QLPTLEMALSLIYGL----------------------KI 346
            ...:..||||:....:.|...     .:..:.:..:|:..|                      .|
  Fly   141 ANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSI 205

  Fly   347 QQNVFKYLPELIYLDLSHSKMTRNSAVAFAHLGDKLKFLSLCYTAIPMVSSTIFKNTVLEGLDLS 411
            |..||:.:..:..::||::::.......||... .|:.|.|.|..:.....|  :..::..|.|.
  Fly   206 QPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAA-SLENLVLSYNELKNFQLT--EKNIVHQLHLD 267

  Fly   412 GNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKNLQVLGLAGNNINALTPAMFQSLE 476
            .| ||:...|        |..:::....:.|.:|...:|| :::.|.|:.|.::::  :...::.
  Fly   268 NN-YLTNLTI--------NATRFVRASHNQISELFLHQSL-HIETLDLSANKLSSI--SNITNIT 320

  Fly   477 SLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNEMLKDFERLDYLSLGDND------ 535
            .:..||:|.|.:|....|.|.....||.||||...|..|...|....:.|:.|.|..|:
  Fly   321 HMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNL 385

  Fly   536 ------------FICDCHLRAVVEVAAANN-KDADCSYRLLNYSQNAVGEEVI-------SLAES 580
                        |:.|.:  .:.|:..... .:|....:.|..|:|......:       ||.||
  Fly   386 DMFVPYLTNLKKFLIDGN--GLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPES 448

  Fly   581 LII----DRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLDGD 641
            :::    |..|.::.:|    |..|.|   :::..::...|::|                  :..
  Fly   449 VVLNIEPDTNLDETPHI----RDVSCI---SQSQEVVNASFTAE------------------ESK 488

  Fly   642 LTLKFQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIA-VMGS--LVGACI 703
            |..:.|:|              ..|:|.:....:::     |||.....:.| |||.  |||...
  Fly   489 LESQIQML--------------SKQLDIVGSHSKNL-----ELHLAFMQIFAYVMGGLVLVGVVS 534

  Fly   704 LGFIIYLKRWHIHYYYSSLKSAALLSSASKES 735
            |..:.|||......|..|  |....|:|:.|:
  Fly   535 LITLRYLKNQRSGRYDRS--SIVFRSNATMEA 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	84/392 (21%)
		leucine-rich repeat	264..287	CDD:275380	8/22 (36%)
		leucine-rich repeat	288..311	CDD:275380	5/22 (23%)
		leucine-rich repeat	312..356	CDD:275380	11/70 (16%)
		leucine-rich repeat	357..381	CDD:275380	4/23 (17%)
		leucine-rich repeat	382..397	CDD:275380	4/14 (29%)
		leucine-rich repeat	405..430	CDD:275380	6/24 (25%)
		leucine-rich repeat	432..453	CDD:275380	4/20 (20%)
		leucine-rich repeat	454..477	CDD:275380	3/22 (14%)
		leucine-rich repeat	478..501	CDD:275380	7/22 (32%)
		leucine-rich repeat	502..525	CDD:275380	9/22 (41%)
		TIR	751..891	CDD:214587
CG4950	NP_648855.2	LRR	96..411	CDD:443914	72/331 (22%)
		leucine-rich repeat	96..119	CDD:275380	8/22 (36%)
		leucine-rich repeat	120..143	CDD:275380	5/22 (23%)
		leucine-rich repeat	144..167	CDD:275380	5/22 (23%)
		leucine-rich repeat	168..191	CDD:275380	2/22 (9%)
		leucine-rich repeat	192..215	CDD:275380	4/22 (18%)
		leucine-rich repeat	216..239	CDD:275380	4/23 (17%)
		leucine-rich repeat	240..299	CDD:275380	16/70 (23%)
		leucine-rich repeat	300..321	CDD:275380	3/22 (14%)
		leucine-rich repeat	322..345	CDD:275380	7/22 (32%)
		leucine-rich repeat	346..365	CDD:275380	9/18 (50%)
		leucine-rich repeat	370..394	CDD:275380	4/23 (17%)
		leucine-rich repeat	395..420	CDD:275380	4/26 (15%)