DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-9 and CG18480

DIOPT Version :9

Sequence 1:NP_001246846.1 Gene:Toll-9 / 40245 FlyBaseID:FBgn0036978 Length:900 Species:Drosophila melanogaster
Sequence 2:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster


Alignment Length:474 Identity:98/474 - (20%)
Similarity:155/474 - (32%) Gaps:180/474 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   317 LSFTNFLTYSYQLQLPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFA----- 376
            |.....|.|...|....|::..|     |.|..:|  .|.:.:.|| |::  ||.||..|     
  Fly    13 LGLKQILLYVGLLLCVLLQVCRS-----KTQSQMF--CPTVCHCDL-HAQ--RNRAVCSAKRLIS 67

  Fly   377 ---HLGDKLKFLSLCYTAIPMVSSTIFKNTV-LEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYF 437
               .:...::.|.|.|..|..:....||.|: |..|.|:.|..  :.:..|||            
  Fly    68 ANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAI--HTLYGDAF------------ 118

  Fly   438 ERSNIKDLEWSKSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSAL 502
                       ..|..|:.|.|:.|.:..:...:.:|...|..|:|..|.:....:.....:.:|
  Fly   119 -----------VELTRLRYLDLSYNRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPILRSPSL 172

  Fly   503 RVLNLRSNTINMLSNEMLKDFERLDYLSL----------GD--------------NDFICDCHLR 543
            |.||||::.:|.|..::|....:|..|.|          ||              |.|.||   |
  Fly   173 RSLNLRNSQVNQLGTQLLSALPQLRQLDLAQNLLLTLSPGDFHAPRNLASLNVEENPFNCD---R 234

  Fly   544 AVVEVAAANNKDADCSYRLLNYSQNAVGEEVISL---AESLIIDRKLWQSRYIPWLQRSYSNIRE 605
            |:.:||....:..     :..:..|.:.|||...   ||::                 ::.|..|
  Fly   235 ALAKVATGLRQRG-----VAIFMSNCMEEEVQDHQDDAEAV-----------------NFPNKNE 277

  Fly   606 FNRANHIIKLRFSSEDYMVAKCSAAQPYHLG---------DLDGDLTLKFQLLDYEASQYYCFNN 661
                      :|.|.:|:       :|...|         |||..                  ..
  Fly   278 ----------KFESMEYL-------EPSTRGPQSVLSVWRDLDSS------------------EE 307

  Fly   662 TDQLQVDELNCQIRSMSDLAEE------------LHHVTNTVIA--------------------- 693
            .:..|.||   |:.|:||:.|.            |..|::.::|                     
  Fly   308 QNSSQDDE---QMSSLSDVCEGSREKLCLRYRICLERVSHELLAGGNSQLEDEIIRTHTYDEDDL 369

  Fly   694 ----VMGSLVGACILGFII 708
                |:|...|.|::.|||
  Fly   370 KLAFVVGGATGVCMVIFII 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-9NP_001246846.1 leucine-rich repeat 157..185 CDD:275380
LRR_8 262..322 CDD:290566 1/4 (25%)
leucine-rich repeat 264..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..356 CDD:275380 9/38 (24%)
LRR_8 <344..387 CDD:290566 13/50 (26%)
leucine-rich repeat 357..381 CDD:275380 8/31 (26%)
leucine-rich repeat 382..397 CDD:275380 4/14 (29%)
leucine-rich repeat 405..430 CDD:275380 7/24 (29%)
LRR_8 431..488 CDD:290566 10/56 (18%)
leucine-rich repeat 432..453 CDD:275380 1/20 (5%)
LRR_RI <449..536 CDD:238064 25/110 (23%)
leucine-rich repeat 454..477 CDD:275380 5/22 (23%)
LRR_8 477..536 CDD:290566 19/82 (23%)
leucine-rich repeat 478..501 CDD:275380 4/22 (18%)
leucine-rich repeat 502..525 CDD:275380 9/22 (41%)
TIR 751..891 CDD:214587
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 19/84 (23%)
LRR_RI <76..230 CDD:238064 39/178 (22%)
leucine-rich repeat 76..99 CDD:275380 7/22 (32%)
leucine-rich repeat 100..123 CDD:275380 8/47 (17%)
LRR_8 122..182 CDD:290566 15/59 (25%)
leucine-rich repeat 124..147 CDD:275380 5/22 (23%)
leucine-rich repeat 148..171 CDD:275380 4/22 (18%)
LRR_8 170..230 CDD:290566 15/59 (25%)
leucine-rich repeat 172..195 CDD:275380 9/22 (41%)
leucine-rich repeat 196..219 CDD:275380 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453682
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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