DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Toll-9 and Tehao

DIOPT Version :10

Sequence 1:NP_649214.1 Gene:Toll-9 / 40245 FlyBaseID:FBgn0036978 Length:900 Species:Drosophila melanogaster
Sequence 2:NP_477438.1 Gene:Tehao / 34761 FlyBaseID:FBgn0026760 Length:795 Species:Drosophila melanogaster


Alignment Length:717 Identity:158/717 - (22%)
Similarity:287/717 - (40%) Gaps:169/717 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   248 SSSQSIAWATFPKMPRLVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQG- 311
            |..::|....|..:|.|.:....: .:..:.:..|.....||.|.:|.| :.|:..:....|.| 
  Fly   146 SQPENITTWHFGSVPGLKKFKFFS-HVPELQESIFHGFDTLRDLHLSVN-VTTLPGNMLSTVNGT 208

  Fly   312 VQYLDL------SFTNFLTYSYQLQLPTLEMALSLIYGL-----KIQQNVFKYLPELIYLDLSHS 365
            ::.|.:      ||.|.|....| ||..|  :|:||:..     ::|.:.|             .
  Fly   209 LKTLTIESPGIVSFGNPLLRELQ-QLRNL--SLALIHPFHERDKQLQPHFF-------------G 257

  Fly   366 KMTRNSAVAFAHLGDKLKFLSLCYTAIPMVSSTIFKNT-VLEGLDLSGNPYLSYNIIDDAFDGIA 429
            .||....|..|             :|...|:.::||.| .|:.:.::||            |.:.
  Fly   258 SMTNLEEVRLA-------------SATSSVNRSMFKGTNKLQLIKMNGN------------DDLM 297

  Fly   430 NTLKYLYFERSNIKDLEWSKSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRS 494
            .....::.::.|:|.|:            |:.|.|..|...:|:.|.:|.:||||.|.:.|...:
  Fly   298 ELPGEIFLDQVNLKTLD------------LSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSST 350

  Fly   495 AFHNNSALRVLNLRSNTINMLSNEMLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANN-----K 554
            .|...::|.||.|..|::..:|..:.:|...|:|:.:.:..|.....|.....|...|:     |
  Fly   351 IFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYK 415

  Fly   555 DAD--CSYRLLNYSQNAVGEEVISLAESLIIDRKLWQSRYIPWLQR----------------SYS 601
            .|:  |..|.:.:.|.:||        |||:|.:......:|.|.|                |..
  Fly   416 SAEWQCDPRCICWVQRSVG--------SLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLP 472

  Fly   602 NIREFNRANHIIKLRFSSEDYMVAKCSAAQ-PYHLGDLD------GDLTLKFQLLDYEASQYYCF 659
            .:.|.:...::..| |.|::.:.:..|..| |.:|..||      ..|:.:|.|...|.      
  Fly   473 TVSEHSGYANVSGL-FLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEP------ 530

  Fly   660 NNTDQLQV--DELNCQIRSMS-------------DLAE-------------ELHHVTNTVIAVMG 696
            |||..|.:  :.:.|...|:|             |:|:             |...:..:.:.::.
  Fly   531 NNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLIS 595

  Fly   697 SLVGA-----CILG--FIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIF 754
            .:||.     |:|.  ::::.:...|..|.::|    .|...|:|.::|         ...||.|
  Fly   596 CVVGGLVIVICLLTVFYLMFQQELKIWLYNNNL----CLWWVSEEELDK---------DKTYDAF 647

  Fly   755 ISYCQNDRTWVLNELLPNVEE-TGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLL 818
            |||...|.. ::::|||.:|. .....:|||:||:.:|..|.:.|:..:|.|..:::::|..|:.
  Fly   648 ISYSHKDEE-LISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFID 711

  Fly   819 SHWCQFEMYLAQHRIFEVSKEHLILVFLEDIPRRKR-PKTLQYLMDVKTYIKWPTAKEDRKLFWK 882
            |.|.:.|..:|.....:..::.:|::...::..... ...|:..:.:.||:||     ...|||.
  Fly   712 SVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKW-----GDPLFWS 771

  Fly   883 RL 884
            :|
  Fly   772 KL 773

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-9NP_649214.1 LRR 198..537 CDD:443914 67/301 (22%)
leucine-rich repeat 264..287 CDD:275380 2/22 (9%)
leucine-rich repeat 288..311 CDD:275380 7/22 (32%)
leucine-rich repeat 312..356 CDD:275380 14/54 (26%)
leucine-rich repeat 357..381 CDD:275380 4/23 (17%)
leucine-rich repeat 382..397 CDD:275380 2/14 (14%)
leucine-rich repeat 405..430 CDD:275380 4/24 (17%)
leucine-rich repeat 432..453 CDD:275380 3/20 (15%)
leucine-rich repeat 454..477 CDD:275380 6/22 (27%)
leucine-rich repeat 478..501 CDD:275380 8/22 (36%)
leucine-rich repeat 502..525 CDD:275380 7/22 (32%)
TIR 751..891 CDD:214587 37/136 (27%)
TehaoNP_477438.1 LRR 184..>541 CDD:443914 98/425 (23%)
leucine-rich repeat 185..207 CDD:275380 7/22 (32%)
leucine-rich repeat 209..232 CDD:275380 6/23 (26%)
leucine-rich repeat 233..261 CDD:275380 8/42 (19%)
leucine-rich repeat 262..284 CDD:275380 7/34 (21%)
leucine-rich repeat 285..309 CDD:275380 4/35 (11%)
leucine-rich repeat 310..333 CDD:275380 8/34 (24%)
leucine-rich repeat 334..357 CDD:275380 8/22 (36%)
leucine-rich repeat 358..381 CDD:275380 7/22 (32%)
leucine-rich repeat 445..482 CDD:275380 5/36 (14%)
leucine-rich repeat 483..505 CDD:275380 6/22 (27%)
TIR 643..779 CDD:214587 37/137 (27%)

Return to query results.
Submit another query.