Protein Alignment Toll-9 and Toll-9

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_565221.3
• Gene: Toll-9 / 3290281
• VectorBaseID: AGAMI1_015050
• Length: 817
• Species: Anopheles gambiae
• Alignment Length: 834
• Identity: 257/834 - (30%)
• Similarity: 398/834 - (47%)
• Gaps: 167/834 - (20%)

  Fly    72 CLLDLIKDEVIWWQFPNGTLRDSTKKYAHKLYLDLSHGNLKDDSDLFREAKLSRKVTIWRTEVFS 136
            |||. ..:..:.|...:|.|......:|    ||||...|.|.........:|..:.:......|
Mosquito   129 CLLG-TANNYLPWVTEDGRLTVRPGPHA----LDLSSLRLSDHGVQGLVQGVSALIPLEEVLHLS 188

  Fly   137 AAFNTLTAAPFRTLYSMRESLKLLSLRGNNFAELIPDAEDFARFVNESRLEASNSVPHHCELLLL 201
            .|.|.||..|..||... ::::||||.||.|.|.                  ||....|..|
Mosquito   189 IARNELTLVPSPTLKKF-QNVRLLSLSGNFFTEF------------------SNDTAEHNRL--- 231

  Fly   202 HNTTDLYDRECYLYFNNNTNMGQSITTGRNYTNFIKVLKDRFDQHGSSSQSIAWATFPKMPRLVE 266
                                                                     |.:.:|..
Mosquito   232 ---------------------------------------------------------PLLTKLRV 239

  Fly   267 LDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLS-FTNFLTYSYQLQ 330
            ||:.|||:..:.:..|||| ||..||:|.|:|.|:..:.||.::.:.:|||| .....|...:::
Mosquito   240 LDMRNCSLRTLPEAFFRNV-NLEYLFLSHNRITTLPAEIFYPLRSLLHLDLSNMDTRRTGEERIE 303

  Fly   331 LPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFAHLGDKLKFLSLCYTAIPMV 395
            .|.::    ||.|:.:.|::|..|..|::||||::::...:.:|...:..:::::|.|...:|.:
Mosquito   304 NPFMK----LIAGVDLHQDIFFPLISLVFLDLSNTRLEYQAFIALRSVQWRVQYVSYCNIGLPAI 364

  Fly   396 SSTIFKNTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKNLQVLGLA 460
            ...:|.:..:..||:|.|..::.::...:|..:|::|:.|||:.|.::.|.|...|:.|:||.|.
Mosquito   365 VDYLFVSKKIAMLDISYNVGVAQSLHSASFTLLADSLEVLYFKDSMVQQLNWLVPLQRLRVLNLR 429

  Fly   461 GNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNEMLKDFER 525
            ||.:..|....|.:|..||.||||.|::..|.:......:||:.:|||:|:|.:|:.:||.||.|
Mosquito   430 GNILRMLQRESFANLTHLEQLDLSYNYISAWNQQILTTTTALQSVNLRNNSIVILTTDMLYDFSR 494

  Fly   526 LDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLNYSQNAVGEEVISLAESLIIDRKLWQS 590
            |..:.||.|...|.|:....:.....|..|...:|.:              .||.||:.|:
Mosquito   495 LSAMGLGGNTIQCSCNYVKFLRNILHNRTDVAGAYTI--------------SAEPLIVGRR---- 541

  Fly   591 RYIPWLQRSYSNIREFNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLDGDLTLK-FQLLDYEAS 654
                                                       ..|.:...|:|: .||.|||.|
Mosquito   542 -------------------------------------------GSGTISNKLSLQHVQLFDYEES 563

  Fly   655 QYYCFNNTDQLQVDEL---NCQIRS----MSDLAEE-----LHHVTNTVIAVMGSLVGACIL--G 705
            :|.|.|.|...::|.|   :|.|..    .||:.||     .|...:|::.::.|:..:.::  |
Mosquito   564 EYLCMNFTSNQKLDPLELQDCMIPEDELINSDIPEEGEDEPAHAKNHTLVYILVSVAVSFLILTG 628

  Fly   706 FIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQNDRTWVLNELL 770
            ..::...:||.|::..:|::|:||..:.|.:....:...::....||:|:||...||:|||:.||
Mosquito   629 VGLFYYWFHIKYFFKIMKNSAVLSFFNDEKLYLDKSGLLKEADFHYDVFVSYSNADRSWVLDHLL 693

  Fly   771 PNVEETGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFEMYLAQHRIFE 835
            ||:|....:::|||||||::|..||:|||||||||..||||:|..|||||||||||:|||||:.|
Mosquito   694 PNMEGVSQINLCLHERDFEVGYGILENIISCMDRSRCLMLIVSESFLLSHWCQFEMHLAQHRLLE 758

  Fly   836 VSKEHLILVFLEDIPRRKRPKTLQYLMDVKTYIKWPT-AKEDRKLFWKRLKRSL 888
            ..::.||||.||||||||.||||.||:..|||||||| :..::.||||||.::|
Mosquito   759 TCRDELILVLLEDIPRRKCPKTLSYLLKTKTYIKWPTKSVHEQALFWKRLHKTL 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	92/339 (27%)
		leucine-rich repeat	264..287	CDD:275380	10/22 (45%)
		leucine-rich repeat	288..311	CDD:275380	9/22 (41%)
		leucine-rich repeat	312..356	CDD:275380	12/44 (27%)
		leucine-rich repeat	357..381	CDD:275380	6/23 (26%)
		leucine-rich repeat	382..397	CDD:275380	3/14 (21%)
		leucine-rich repeat	405..430	CDD:275380	5/24 (21%)
		leucine-rich repeat	432..453	CDD:275380	8/20 (40%)
		leucine-rich repeat	454..477	CDD:275380	9/22 (41%)
		leucine-rich repeat	478..501	CDD:275380	8/22 (36%)
		leucine-rich repeat	502..525	CDD:275380	11/22 (50%)
		TIR	751..891	CDD:214587	89/139 (64%)
Toll-9	XP_565221.3	None