DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Toll-9 and AT2G20142

DIOPT Version :9

Sequence 1:	NP_001246846.1	Gene:	Toll-9 / 40245	FlyBaseID:	FBgn0036978	Length:	900	Species:	Drosophila melanogaster
Sequence 2:	NP_973487.2	Gene:	AT2G20142 / 2745551	AraportID:	AT2G20142	Length:	313	Species:	Arabidopsis thaliana

Alignment Length:	291	Identity:	71/291 - (24%)
Similarity:	100/291 - (34%)	Gaps:	95/291 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 NKIMTISHDTFYYVQGVQYLDLSFTNFL----------TYSYQLQLPT---LEMALSLIYGLKIQ 347
            |....:.||.|...:.....| :|.:.|          |:.|. :||.   .|.:|..|...||.
plant     2 NSSPKMKHDVFISFRSKDTRD-NFVSHLCGCLRRKRIKTFLYD-ELPADERYEESLKAIEVSKIS 64

  Fly   348 QNVFK--------------------------YLPELIYLD-LSHSKMTRNSAVAFAHLGDKLKFL 385
            ..||.                          .:|.|.::| |.....|.:...|||...||.:.|
plant    65 VIVFSENFGDSRWCLDEVVAILKCKEKFGQIVIPVLYHVDPLDIENQTGSFGDAFAKRRDKAEQL 129

  Fly   386 SLCYTAIPMVSSTIFKNTVLEGLDLSG--NPYLSYNIIDDAF--DGIANTL--KYLYFERSNIKD 444
            .            .:|::..|.::|.|  ..|||    |:..  :|||..:  |.|...|:.:.
plant   130 Q------------EWKDSFTEAINLPGWSTAYLS----DEEMLVNGIAREIENKLLRASRTKVM- 177

  Fly   445 LEWSKSLKNLQV---------LGLAGNNINALTPAMFQSLES--LEILDLSSNHVG--------- 489
            :|||..:.||.:         :..|...:.||. ||..||.|  |.|:||.  |.|
plant   178 IEWSLVITNLMLEIPSSVFDQISSAHKPLYALA-AMSMSLLSCLLCIVDLL--HKGRVDRVVWKW 239

  Fly   490 NWYRSAFHNNSALRVLNLRSNTINMLSNEML 520
            .|....||..:.      |||...... |||
plant   240 TWPIPWFHYQTQ------RSNRFGSFP-EML 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_001246846.1	leucine-rich repeat	157..185	CDD:275380
		LRR_8	262..322	CDD:290566	6/25 (24%)
		leucine-rich repeat	264..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380	4/14 (29%)
		leucine-rich repeat	312..356	CDD:275380	14/82 (17%)
		LRR_8	<344..387	CDD:290566	15/69 (22%)
		leucine-rich repeat	357..381	CDD:275380	7/24 (29%)
		leucine-rich repeat	382..397	CDD:275380	1/14 (7%)
		leucine-rich repeat	405..430	CDD:275380	9/28 (32%)
		LRR_8	431..488	CDD:290566	20/69 (29%)
		leucine-rich repeat	432..453	CDD:275380	6/22 (27%)
		LRR_RI	<449..536	CDD:238064	25/92 (27%)
		leucine-rich repeat	454..477	CDD:275380	8/31 (26%)
		LRR_8	477..536	CDD:290566	16/55 (29%)
		leucine-rich repeat	478..501	CDD:275380	9/31 (29%)
		leucine-rich repeat	502..525	CDD:275380	6/19 (32%)
		TIR	751..891	CDD:214587
AT2G20142	NP_973487.2	TIR	9..168	CDD:279864	39/176 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010