Protein Alignment Toll-9 and LOC1270742

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_061512545.1
• Gene: LOC1270742 / 1270742
• VectorBaseID: AGAMI1_005130
• Length: 1369
• Species: Anopheles gambiae
• Alignment Length: 1114
• Identity: 228/1114 - (20%)
• Similarity: 395/1114 - (35%)
• Gaps: 363/1114 - (32%)

  Fly    55 TDLKSLMLKYESDDGN-------SC-----LLDLIKDEVIWWQFPNGTL------------RDST 95
            :||..|||   ||.||       :|     :|||..:::.  ..|:..|            |:..
Mosquito   112 SDLTQLML---SDWGNGPTEPGRACNTGLEVLDLSGNDLT--LLPDNGLTAMRSLNALHLQRNLL 171

  Fly    96 KKYAHKLYLDLSHGNLKDDSD---------LFREAKLSRKVTIW----------------RTEVF 135
            |:.|.:.::.|....:.|.||         ||..::..|:|.:.                |.|..
Mosquito   172 KEIADRAFVGLGTLEVLDLSDNRLTALTPELFVSSRKIRQVYLQNNSLSVLAPGVFEGLDRLETL 236

  Fly   136 SAAFNTLTAA-----------------------------PFRTLYSMRESLKLLSLRGNNFAELI 171
            ..:.|.||:.                             .|:.||    ||::|:|. :|..||:
Mosquito   237 DLSRNQLTSTWVKRDTFAGQVRLVVLNLGHNQLSKVDQHVFKGLY----SLQILNLE-HNAIELL 296

  Fly   172 PDA--EDF----ARFVNESRLEASNSVPHH-CELLLLH------------------NTTDLYDRE 211
            .|.  .|.    |.|::.:||....  |:| .||.:|:                  |.|.|:|
Mosquito   297 ADGAFSDLKNLHALFLSHNRLRQIE--PYHFSELYVLNQLILESNQIAYIHERAFENLTHLHD-- 357

  Fly   212 CYLYFNNNTNMGQSITTGRNYTNFIKVL---KDRFDQHGSSS-----------------QSIAWA 256
                .:.|.|..:.|.:|.....|::.|   |::..:..:||                 ..|:..
Mosquito   358 ----LSLNDNRLEEIPSGMKSLKFLQSLDLGKNQIAEINNSSFEGLEELMGLRLVDNQISEISRD 418

  Fly   257 TFPKMPRLVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLSFTN 321
            ||..:..:..|::::..|.::.:.||.:...||.:.:.:|::..:| ..|..:..:.||::|..|
Mosquito   419 TFFALSTIHVLNLASNRIRHIDQSAFSSNPTLRAIRLDNNELEDVS-GVFTSLSSLVYLNISDNN 482

  Fly   322 --FLTYS-YQLQLPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFAHLGDKL- 382
              :..|| |...|..|::..:.|..|..:.:|..:. :|..||:||:|:.:.:|.:|.|..:.:
Mosquito   483 IGWFDYSHYPQSLEWLDIHKNNISELGNRYDVGNWF-QLKMLDVSHNKLRQINASSFPHNIETIL 546

  Fly   383 -------KFLSLCYTAIPMVSSTIFKNTVLEGLDLSG---NP----------YLSYNII--DDAF 425
                   :.....:|....:...:.....|..:::|.   .|          ||..|:|  |...
Mosquito   547 MNNNHIEEIAPETFTGKEHIVKVVLYGNRLRRIEMSALALTPWPDTRMLPEFYLGDNLIHCDCTM 611

  Fly   426 DGI--ANTLKYLYFERSNIKDLE------------------------------------------ 446
            :.:  .|.|.||. :...:|||:
Mosquito   612 EWLQRINELAYLR-QYPQVKDLDSVHCSMEHERGEQRRPLMAMRASEFLCRYEAHCFATCHCCDF 675

  Fly   447 --------------------WSKSLKNLQVLGLA----------------GNNINALTPAMFQSL 475
                                |..::.:....||:                |||:.||...:|...
Mosquito   676 DACDCKMACPDRCRCYHDTAWESNIVDCGSAGLSLVPAKIPMDATDIYLDGNNLGALGSHVFIGK 740

  Fly   476 ESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSN---EMLKDFERLDYL------SL 531
            :.|:.|.|:.:.:.:.....|....||.||:|..|.:..||.   |.|::.:.| ||      |:
Mosquito   741 KKLKSLYLNGSRIESLNNKTFAGIPALEVLHLEQNGLEQLSGAEFEQLRELKEL-YLHRNALASI 804

  Fly   532 GDNDFICDCHLRAVVEVAAANNK---------------DADCSYRLLNYSQNAVGEEVISLAESL 581
            |:..|.   :.:::..:..|.||               ..|.:||.::...||: |....|...|
Mosquito   805 GNRSFY---YQKSLEVLTIAENKLKGVRPWELLPLPSGGPDGAYRSVSLEGNAL-ECSCELLPKL 865

  Fly   582 IIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSED--YMVAKCSAAQPYHLGDLDGDLTL 644
                       :.||:|.|   |....|....:...|||:  :...:|:..:|  |.|:
Mosquito   866 -----------LDWLERMY---RSNGSAAQSEEQTESSEETSWGEFQCAGGKP--LPDV------ 908

  Fly   645 KFQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTV------------IAVMGS 697
                                  |.|...|..::..:|...  |..|:            |||:..
Mosquito   909 ----------------------VKECEGQRPAVVPVATAT--VQRTIINDDFIDYLPLLIAVLAG 949

  Fly   698 LVGACILGFIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQ-RDPSAVYDIFISYCQND 761
            ||...:|..::.|.|..:..:..|.....|..       :..|.:.: .|...:||.::.|...|
Mosquito   950 LVLTIMLVALVVLFRQDVCLWAHSRYGVRLCK-------DPLTALERCEDSEKLYDAYLLYSAAD 1007

  Fly   762 RTWVLNELLPNVEETGDVSICLHERDFQIGVTIL-DNIISCMDRSYSLMLIISSKFLLSHWCQFE 825
            ...|.:::...:|..| ..:|||.||...|...| |.:.|..|.|..|:|.:|.|||...|.|.|
Mosquito  1008 ADLVTSQIGQELEHHG-YGMCLHYRDVHGGAGFLGDTVQSAADASRKLVLFVSVKFLQLEWSQPE 1071

  Fly   826 MYLAQHRIFEV---SKEHLILVFLEDIPRRKRPKTLQYLMDVK----TYIKWPTAKEDRKLFWKR 883
            ...|.....|:   |:....:|.:..:|...  ..:..:||:.    |.|.|    :||: ||.:
Mosquito  1072 FRAALQAALELIRPSRRKQRIVLITSVPGSM--LAMDPIMDILARTCTVIAW----DDRR-FWDK 1129

  Fly   884 LKRSLEVIG 892
            |:.::..:|
Mosquito  1130 LRFAMPDLG 1138

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	92/491 (19%)
		leucine-rich repeat	264..287	CDD:275380	4/22 (18%)
		leucine-rich repeat	288..311	CDD:275380	5/22 (23%)
		leucine-rich repeat	312..356	CDD:275380	12/46 (26%)
		leucine-rich repeat	357..381	CDD:275380	9/23 (39%)
		leucine-rich repeat	382..397	CDD:275380	1/22 (5%)
		leucine-rich repeat	405..430	CDD:275380	8/41 (20%)
		leucine-rich repeat	432..453	CDD:275380	7/82 (9%)
		leucine-rich repeat	454..477	CDD:275380	8/38 (21%)
		leucine-rich repeat	478..501	CDD:275380	4/22 (18%)
		leucine-rich repeat	502..525	CDD:275380	9/25 (36%)
		TIR	751..891	CDD:214587	42/147 (29%)
LOC1270742	XP_061512545.1	None