Protein Alignment Toll-9 and tlr21

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_002936443.3
• Gene: tlr21 / 100497009
• XenbaseID: XB-GENE-5956980
• Length: 937
• Species: Xenopus tropicalis
• Alignment Length: 911
• Identity: 209/911 - (22%)
• Similarity: 335/911 - (36%)
• Gaps: 286/911 - (31%)

  Fly   215 YFNNNTNMGQSITTGR-NYTNFIKVLKDRFDQHGSSSQSIAWATFPKMPRLVELDISNCSIEYVS 278
            |.|.:.|..|::..|. .:..|::.|:...:|    .|.:....|..:..|.:|.:|:..|..:|
 Frog    59 YLNISYNNIQTLHQGSFGHMPFLRTLRLNHNQ----LQRLDPGAFENLTMLEKLHLSSNKISNLS 119

  Fly   279 KEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLSFTNFLTYSYQLQ-------LPTLEM 336
            ||.|..:.|:..||:.||.:.:|..:.|.::..:|.|:||..|...:...:|       |.||.:
 Frog   120 KEVFCGLQNVSWLFLDDNLLSSIHPEAFSHLTNLQNLNLSMNNLHNFEKVVQSIHPLQKLNTLML 184

  Fly   337 ALSLIYGLK-----------------------IQQNVFKYLPELIYLDLSHSKMTRNSA------ 372
            ..:.|..|.                       .||:.|.   .:.:||||::.:..:|.
 Frog   185 CSNQISSLNHTHRLPSTLRWLFLCKNQLATLDCQQDFFL---NISWLDLSYNNIATSSLQTMDLR 246

  Fly   373 ------VAFAHLGDKLKFLS--------LCYTAIPMVSSTIFKN--TVLEG-----LDLSGNPYL 416
                  |||....|.|.|:.        :.|:.:.:.:.:..|.  ..|:|     |.||||...
 Frog   247 KVIYLNVAFNGNFDILIFIKNPTVPINRIDYSGLNLNNDSKLKTMCRYLKGFNINTLYLSGNKIK 311

  Fly   417 SYN-------IIDDAFDGIANTLKYL----YFERSNIKDLEWSKSL------------------- 451
            :.|       .::...|...|.||.|    :..::|:::|....:|
 Frog   312 TLNRGTLTDCPLNKTLDLSRNRLKGLGCLEFMSKTNVENLIVEHNLLKELINCSKKSHFPRLRHI 376

  Fly   452 ------------------KNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHN 498
                              .|||.|.|..|||..|....|..|..|..|.|.:|.:.:.|.::|.|
 Frog   377 SFRYNRIWIVKGNAFHFAPNLQTLYLNINNIVFLERYSFSGLGKLRELRLDNNLITDLYENSFAN 441

  Fly   499 NSALRVLNLRSNTINMLSNEMLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLL 563
            .:.||:||||:|.::::.:::..:..:|..|.||.|            ::....|:.   .|.|.
 Frog   442 LTELRILNLRNNRVSVIFSKVFYNLGKLTTLDLGGN------------KITQLKNQS---FYGLR 491

  Fly   564 NYSQ--------NAVGEEVISLAES--LIIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFS 618
            :.|:        ..:...|.|..||  |::|.|....|| ...:.:||.....::...:
 Frog   492 SLSKLYLDGNQIKEISRYVFSHVESTLLVLDLKSNHLRY-NTTRETYSPFLTLSKLYDL------ 549

  Fly   619 SEDYMVAKCSAAQPYHL-----GDLDGDLTLK--------------------------------- 645
                   |..|.|||.|     |...|..:||
 Frog   550 -------KLQAQQPYGLTAIPQGFFKGLKSLKALYLAQNRISSLSSDAFNELGQLTYLSLAEDCN 607

  Fly   646 ---------------FQLLDYE--ASQYY---------------------------CFNNTDQLQ 666
                           .|:||.|  ..||.                           .|.|..||:
 Frog   608 GIQRLPPGIFKNLKNLQILDLENICLQYMRMEVFSSLTNLKRLLLTKNALTHINIKVFENMTQLK 672

  Fly   667 -VDELNCQIRSMSDLAE-------------------------ELHHVTNTVIAVMGSLVG----- 700
             :|...|.:....:.||                         ...|..:|.:..|...:.
 Frog   673 YLDLRKCPLSCTCNNAELQMWFKKGPVQIVLPYNLTCPANENSYFHDFDTHVCDMEIKIKLFCSS 737

  Fly   701 -ACILGFII----YLK-RWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQ 759
             ..||.|||    |.| .|.|.|.|  ....|.|....|.....:.          ||.|:||..
 Frog   738 FTSILLFIIIPIVYSKFYWMIKYNY--FLFVAWLHERWKSEKELYK----------YDAFVSYNT 790

  Fly   760 NDRTWVLNELLPNVEETGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQF 824
            :|..||...:|| |.||..:.:|||.||||:|..|:|||:..:..|...:.::|..:|.|.||..
 Frog   791 HDEEWVYKIMLP-VLETSALRLCLHHRDFQLGRDIIDNIVDSIHNSRKTICVVSRSYLQSEWCSL 854

  Fly   825 EMYLAQHRIFEVSKEHLILVFLEDIPRRKRP--KTLQYLMDVKTYIKWPTAKEDRKLFWKRLKRS 887
            ||.||.:::|:..::.|:|:.|::||.|:..  ..::.||..||||.|||..|.::|||.:::.:
 Frog   855 EMQLASYKLFDEMRDVLVLILLDNIPDRELSTYHRMRKLMLKKTYITWPTEPEAQQLFWAKVQEA 919

  Fly   888 L 888
            :
 Frog   920 V 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	98/427 (23%)
		leucine-rich repeat	264..287	CDD:275380	8/22 (36%)
		leucine-rich repeat	288..311	CDD:275380	6/22 (27%)
		leucine-rich repeat	312..356	CDD:275380	14/73 (19%)
		leucine-rich repeat	357..381	CDD:275380	8/35 (23%)
		leucine-rich repeat	382..397	CDD:275380	3/22 (14%)
		leucine-rich repeat	405..430	CDD:275380	9/36 (25%)
		leucine-rich repeat	432..453	CDD:275380	6/61 (10%)
		leucine-rich repeat	454..477	CDD:275380	10/22 (45%)
		leucine-rich repeat	478..501	CDD:275380	7/22 (32%)
		leucine-rich repeat	502..525	CDD:275380	7/22 (32%)
		TIR	751..891	CDD:214587	55/140 (39%)
tlr21	XP_002936443.3	LRR_8	59..115	CDD:404697	13/59 (22%)
		leucine-rich repeat	59..80	CDD:275380	5/20 (25%)
		leucine-rich repeat	81..104	CDD:275380	4/26 (15%)
		LRR_8	105..163	CDD:404697	19/57 (33%)
		leucine-rich repeat	105..128	CDD:275380	8/22 (36%)
		leucine-rich repeat	129..152	CDD:275380	6/22 (27%)
		leucine-rich repeat	153..224	CDD:275380	14/73 (19%)
		LRR	212..631	CDD:443914	91/450 (20%)
		leucine-rich repeat	225..299	CDD:275380	15/73 (21%)
		leucine-rich repeat	300..323	CDD:275380	6/22 (27%)
		leucine-rich repeat	348..363	CDD:275378	2/14 (14%)
		leucine-rich repeat	373..396	CDD:275380	0/22 (0%)
		leucine-rich repeat	397..420	CDD:275380	10/22 (45%)
		leucine-rich repeat	421..444	CDD:275380	7/22 (32%)
		leucine-rich repeat	445..468	CDD:275380	7/22 (32%)
		leucine-rich repeat	469..492	CDD:275380	8/37 (22%)
		leucine-rich repeat	493..516	CDD:275380	3/22 (14%)
		leucine-rich repeat	518..572	CDD:275380	15/67 (22%)
		leucine-rich repeat	573..596	CDD:275380	2/22 (9%)
		leucine-rich repeat	597..622	CDD:275380	0/24 (0%)
		LRR_8	622..681	CDD:404697	12/58 (21%)
		leucine-rich repeat	623..646	CDD:275380	6/22 (27%)
		leucine-rich repeat	647..668	CDD:275380	1/20 (5%)
		TIR	781..923	CDD:214587	55/151 (36%)