Protein Alignment Toll-9 and LOC100496647

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_002940742.3
• Gene: LOC100496647 / 100496647
• -ID: -
• Length: 879
• Species: Xenopus tropicalis
• Alignment Length: 991
• Identity: 229/991 - (23%)
• Similarity: 358/991 - (36%)
• Gaps: 314/991 - (31%)

  Fly     9 VIVLVCLFLGNVREAYTEFSIQDGLIIEPDSATTSSEEAEEVSKERTDLKSLMLKYESDDGNSCL 73
            ::.||.|.||:.:        .:.||::.||...:.      |..:.||....|.....||.:.|
 Frog    79 LLQLVDLNLGSQQ--------TERLIVKKDSFRNTP------SLVKLDLAYNQLLILDSDGLAGL 129

  Fly    74 LDLIKDEVIWWQFPNGTL--RDSTKKYAHKLYLDLSHGNLKDDSDLFREAKLSRKVTIWRTEVFS 136
            ..| |...:::...||::  .|..|......|:|||                |.::|..|.
 Frog   130 SQL-KILFLYYNKLNGSILENDYFKDLMSLEYVDLS----------------SNEITYLRP---- 173

  Fly   137 AAFNTLTAAPFRTLYSMRESLKLLSLRGNNFAELIP-DAEDFARFVNESRLEASNSVPHHCELLL 200
               |.|    |..||    ||.:::||.|..:.:.. |...|.|             .:...:.|
 Frog   174 ---NPL----FYHLY----SLDIINLRHNQISSICAGDLHSFER-------------KYFTIMEL 214

  Fly   201 LHNTTDLYDR----ECYLYFNN---NTNM----GQSITTGRNY---TNFIKVLKDRFDQHGSSS- 250
            .||..:.::.    .|...|.|   :|.|    |..:...:.:   .|..|:::.:.|.||..:
 Frog   215 SHNRFNKWETLGSDRCGNPFRNIEFDTLMLSGTGFDVDKMQKFCGALNGTKMMQLKLDSHGMGAG 279

  Fly   251 ------QSIAWATFPKM--PRLVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFY 307
                  :....:||..:  ..|..||:|..:|..:....|.|::.|:.|.:::|||..|.:..|.
 Frog   280 FGYNHIKDPDNSTFVGLVNSNLQILDLSTGNIFSLKPYTFGNLTVLKLLNLAENKINRIENKAFC 344

  Fly   308 YVQGVQYLDLSFTNFL--TYSYQLQ----LPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSK 366
            .:..:..|:||: |.|  .|.|..:    |.|:::..:.|..  ||.|.||.|.:|.||||..:.
 Frog   345 GLNSLITLNLSY-NLLGELYDYSFEGLPDLTTIDLQQNHIGA--IQNNAFKSLEKLNYLDLRGNA 406

  Fly   367 MTR----NSAVAFAHL---GDKLKFLSLCYTAIPMVSSTIFKNTVLEGLDLSGN----------- 413
            |.:    .:.:...::   |:|||.:...|     |.||.        ||||.|
 Frog   407 MKKVTFFEALIPITYIFFGGNKLKSIDSSY-----VYSTF--------LDLSENDLNDLGGLFKI 458

  Fly   414 ---PYLSYNIIDDAFDGIANTLK--YLYFERS------------NIKDLEWSKS-----LKNLQV 456
               |.|.|.|:.      .|.|.  |.:|..|            |:.:|.|...     ..||.:
 Frog   459 LQYPLLQYVILK------RNRLSVCYSHFSISKNNSLLHLDLSDNMINLIWDNGQCLNVFSNLSL 517

  Fly   457 LGLA---GNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNE 518
            |||.   .|.:..|...:|..||||:.|:||||.:.:.....|..|  |..::|..|.:...|.:
 Frog   518 LGLLKLNNNFLRYLPEGIFNGLESLQTLNLSSNLLTHLMPGVFPTN--LDTVDLSKNQLYSPSPK 580

  Fly   519 MLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLNYSQNAVGEEVISLAESLII 583
            :....::||   |..|.:||||.|                                        :
 Frog   581 VFLSVKKLD---LTHNQYICDCFL----------------------------------------L 602

  Fly   584 DRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDY-MVAKCSAAQPYHLGDLDGDLTLKFQ 647
            |       :|.||..:.:.:           |....:.| |.......||.|:      ||::
 Frog   603 D-------FIMWLNETNATL-----------LGSPYDTYCMYPPNFLFQPLHI------LTVE-- 641

  Fly   648 LLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIAVMGSLV-------GAC--- 702
                         |.|..:|         :..|...|..:|:|.|.|:.|.|       |.|
 Frog   642 -------------NCDDDKV---------LMPLMFSLFVLTSTTILVLMSTVVTYTHYRGFCFAT 684

  Fly   703 ---ILGFIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQNDRTW 764
               |||.||                    .:..||         :...:..||.::.|...|..|
 Frog   685 YKRILGLII--------------------GNEKKE---------EAADACKYDAYLCYSSKDFQW 720

  Fly   765 VLNELLPNVE----ETGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFE 825
            |.:..|.|::    :.....:|..||||..|...:.||...:..|...:.|::.:||...||...
 Frog   721 VQDAFLRNLDTQYCDRNRFRLCFEERDFIPGEDHIVNIRDAIWNSKKTICIVTKQFLKDGWCVEA 785

  Fly   826 MYLAQHRIFEVSKEHLILV---------FLEDIPRRKRPKTLQYLMDVKTYIKWPTAKEDRKLFW 881
            :..||.|.|...|:.||:|         |::..|.|...|..|||       :||...:|.:.|.
 Frog   786 LNYAQSRYFTELKDVLIMVVVGSLSQYQFMKYQPIRAYVKRAQYL-------RWPEDIQDVEWFL 843

  Fly   882 KRLKRSLEVIGINSRE 897
            .||  |.:::..|:.|
 Frog   844 GRL--SYQILKENTVE 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	104/410 (25%)
		leucine-rich repeat	264..287	CDD:275380	7/22 (32%)
		leucine-rich repeat	288..311	CDD:275380	7/22 (32%)
		leucine-rich repeat	312..356	CDD:275380	16/49 (33%)
		leucine-rich repeat	357..381	CDD:275380	7/30 (23%)
		leucine-rich repeat	382..397	CDD:275380	4/14 (29%)
		leucine-rich repeat	405..430	CDD:275380	9/38 (24%)
		leucine-rich repeat	432..453	CDD:275380	7/39 (18%)
		leucine-rich repeat	454..477	CDD:275380	8/25 (32%)
		leucine-rich repeat	478..501	CDD:275380	8/22 (36%)
		leucine-rich repeat	502..525	CDD:275380	4/22 (18%)
		TIR	751..891	CDD:214587	44/152 (29%)
LOC100496647	XP_002940742.3	LRR	<60..>196	CDD:443914	39/162 (24%)
		leucine-rich repeat	60..81	CDD:275380	0/1 (0%)
		leucine-rich repeat	82..107	CDD:275380	9/38 (24%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..157	CDD:275380	6/25 (24%)
		leucine-rich repeat	158..182	CDD:275380	12/54 (22%)
		leucine-rich repeat	183..260	CDD:275380	16/89 (18%)
		leucine-rich repeat	261..300	CDD:275380	7/38 (18%)
		LRR	<299..612	CDD:443914	97/386 (25%)
		leucine-rich repeat	301..324	CDD:275380	7/22 (32%)
		leucine-rich repeat	325..348	CDD:275380	7/22 (32%)
		leucine-rich repeat	349..372	CDD:275380	7/23 (30%)
		leucine-rich repeat	373..396	CDD:275380	9/24 (38%)
		leucine-rich repeat	419..446	CDD:275380	11/39 (28%)
		leucine-rich repeat	464..488	CDD:275380	8/29 (28%)
		leucine-rich repeat	489..541	CDD:275380	12/51 (24%)
		leucine-rich repeat	542..563	CDD:275380	7/20 (35%)
		leucine-rich repeat	564..582	CDD:275380	4/17 (24%)
		TIR	706..841	CDD:214587	40/141 (28%)