Protein Alignment Toll-9 and XB5889249

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_017950848.2
• Gene: XB5889249 / 100495326
• XenbaseID: XB-GENE-5889250
• Length: 796
• Species: Xenopus tropicalis
• Alignment Length: 976
• Identity: 220/976 - (22%)
• Similarity: 368/976 - (37%)
• Gaps: 298/976 - (30%)

  Fly     5 YIWDVIVLVCLFLGNVREAYTEFSIQDGLIIE----------PDSATTSSEEAEEVSKERTDLKS 59
            :::.:|:.:          .|:|.....|||:          |...|......|.:    |.||
 Frog    12 FLFAIIIYI----------LTQFESNKALIIQRKLHKCFSSCPSVCTLLDFTKENI----THLK- 61

  Fly    60 LMLKYESDDGNSCLLDL----IKDEVIWWQFPNGTLRDSTKKYAHKL-YLDLSHGNLKDDSDLFR 119
                  :.|.| |.|.|    :...:|      |.|..|..|:...| |||:|:..|       .
 Frog    62 ------TSDFN-CFLQLRLLNLSHNLI------GELDCSVFKFNPSLEYLDISNNRL-------H 106

  Fly   120 EAKLSRKVTIWRTEVFSAAFNTLTAAPFRTLYSMRESLKLLSL-----RGNNFAELIPDAEDFAR 179
            ..|......|...:....::|......|.:.::....||.|.|     :.::|..:.....||..
 Frog   107 TIKCHSLQYIKNIKRMDLSYNNFKTMDFCSEFTALSQLKHLGLSSKKIQKDSFINIASMDLDFVF 171

  Fly   180 FVNESRLEASNSVPHHCELLLLHNTTDLYDRECYLYFNNNTNMGQSITTGRNYTNFIKVLKDRFD 244
            ...|:.:|..|.      .|...||..|:           .|:..:::...:|     :|.|..|
 Frog   172 LGIENEIEYENG------SLQFLNTNKLH-----------INLQPNLSLASSY-----LLSDALD 214

  Fly   245 QHGSSSQSIAWA--------------TFPKMPRLVELDISN-----------------CSIEYVS 278
            .  |.:..::.|              |..|..::|.|.|||                 .|:|::.
 Frog   215 T--SMTLEVSGAQCDVHCDYFTKSFFTINKNSKVVNLIISNSTMPGNEMLKIIPPIWDSSVEHLH 277

  Fly   279 KEAFRNVSNLRRLFMS----DNKIMTI---SHDTFYYVQGVQYLDL---------SFTNF-LTYS 326
            .:.||.:...:.:.|.    ..|..|:   ::|.|:: ||....::         :|:|. :.:.
 Frog   278 IKMFRLIKEFKYVKMDFTHHSIKSFTLEYFTNDVFFF-QGTHPFNIFAEMLVENVTFSNAGMIHF 341

  Fly   327 YQLQLPTLEMALSLIYGLKIQQNVF---KYLPELIYLDLSHSKMTRNSAVAFAHLGDKLKFLSLC 388
            :...:|::...|:|... :|...:|   ..|.||..|:|.::|:.:.|
 Frog   342 FCPPVPSIVRFLNLPSN-RITDEIFLNCSSLNELELLNLQNNKLEQMS----------------- 388

  Fly   389 YTAIPMVSSTIFKNTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKN 453
                 .:||...|...|:.||||.|   ..:|.::......::|.:|....|.:.:..:.....|
 Frog   389 -----KISSMTLKMKNLKHLDLSKN---GLHIDNEKQCNWMDSLVFLNLSESGLTNSVFGCLPIN 445

  Fly   454 LQVLGLAGNNINALTPAMFQSLESLEILDLSSN---------HVGNWYRSAFHNNSALRVLNLRS 509
            ||:|.|:.|.|::: |...::..||:.|.|:||         ::||          .|.||.:..
 Frog   446 LQILDLSKNQISSI-PIEVKNFVSLKELHLASNRLTDIPDCHNIGN----------NLGVLKVDE 499

  Fly   510 NTINMLSNEMLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLNYSQNAVGEEV 574
            |.||:...|.|::.|.:.|||.|.|.|.|:|.||..|::..
 Frog   500 NFINLPPKEFLQNCEYVQYLSAGQNPFQCNCDLREFVKMGV------------------------ 540

  Fly   575 ISLAESLIIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLD 639
                        ::..|.:.|                       .|.|   ||  |.|.::..:
 Frog   541 ------------MFPKRLVGW-----------------------PESY---KC--ADPENVKGI- 564

  Fly   640 GDLTLKFQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIAVMGSLVGAC-- 702
                   .|.|:..|:..|  ||...                  |..|..|:..|...:|.||
 Frog   565 -------FLQDFHLSEISC--NTSLF------------------LGVVLGTIFVVSIIVVSACFY 602

  Fly   703 --ILGFIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRD--PSAVYDIFISYCQNDRT 763
              :..:|..|.||.                   .:.::..|::|:|  ...::..||||.|.|..
 Frog   603 FDVPWYIRMLFRWF-------------------RTKHRLRNVNQQDIQNDKLFHAFISYSQEDSD 648

  Fly   764 WVLNELLPNVE-ETGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFEMY 827
            ||.|.||||:| :.|.:.||.|||.|..|..|::|||.|:::|:..:.::|..|:.|.||.:|:|
 Frog   649 WVKNMLLPNLERKDGSIKICHHERHFIPGKAIIENIIDCIEKSFKSIFVLSPNFIQSDWCHYELY 713

  Fly   828 LAQHRIFEVSKEHLILVFLEDIPRRKRP---KTLQYLMDVKTYIKWPTAKEDRKLFWKRLKRSLE 889
            .|||.:|..:..:|||:.|:.||:...|   ..|:.:|..:||::||..|....|||..|:.::.
 Frog   714 FAQHTLFGKNSNNLILILLDPIPQYSIPNKYNKLRSIMKHRTYLEWPKEKGKHALFWANLREAIH 778

  Fly   890 V 890
            |
 Frog   779 V 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	86/398 (22%)
		leucine-rich repeat	264..287	CDD:275380	9/39 (23%)
		leucine-rich repeat	288..311	CDD:275380	5/29 (17%)
		leucine-rich repeat	312..356	CDD:275380	8/56 (14%)
		leucine-rich repeat	357..381	CDD:275380	5/23 (22%)
		leucine-rich repeat	382..397	CDD:275380	0/14 (0%)
		leucine-rich repeat	405..430	CDD:275380	7/24 (29%)
		leucine-rich repeat	432..453	CDD:275380	3/20 (15%)
		leucine-rich repeat	454..477	CDD:275380	7/22 (32%)
		leucine-rich repeat	478..501	CDD:275380	7/31 (23%)
		leucine-rich repeat	502..525	CDD:275380	8/22 (36%)
		TIR	751..891	CDD:214587	58/144 (40%)
XB5889249	XP_017950848.2	leucine-rich repeat	48..70	CDD:275378	8/33 (24%)
		LRR	<70..229	CDD:443914	37/195 (19%)
		LRR_8	70..129	CDD:404697	15/71 (21%)
		leucine-rich repeat	71..94	CDD:275378	6/28 (21%)
		leucine-rich repeat	95..118	CDD:275378	8/29 (28%)
		leucine-rich repeat	119..143	CDD:275378	2/23 (9%)
		LRR	<396..>526	CDD:443914	41/143 (29%)
		leucine-rich repeat	400..423	CDD:275380	7/25 (28%)
		leucine-rich repeat	424..445	CDD:275378	3/20 (15%)
		leucine-rich repeat	446..468	CDD:275378	7/22 (32%)
		leucine-rich repeat	469..491	CDD:275378	7/31 (23%)
		leucine-rich repeat	492..515	CDD:275378	8/22 (36%)
		leucine-rich repeat	516..528	CDD:275378	6/11 (55%)
		LRRCT	524..576	CDD:214507	18/123 (15%)
		TIR	636..777	CDD:214587	57/140 (41%)