Protein Alignment Toll-9 and tlr20.4

DIOPT Version :10

• Sequence 1: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_073768827.1
• Gene: tlr20.4 / 100005571
• ZFINID: ZDB-GENE-071002-1
• Length: 457
• Species: Danio rerio
• Alignment Length: 627
• Identity: 136/627 - (21%)
• Similarity: 223/627 - (35%)
• Gaps: 208/627 - (33%)

  Fly   270 SNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLSFTNFLTYSYQLQLPTL 334
            ||.|..::|       |.||.:.:......|:::....:::| ||:.:...|.|       |.|.
Zfish    17 SNLSNVFIS-------SGLRPMHLVIGSNTTLNNGLNLHIKG-QYVIVEDCNSL-------LLTS 66

  Fly   335 EMALSLIYGLKIQQNVF--KYLPELIYLDLSHSKMTRNSAVAFA-HLGDKLKFLSLCYTAIPMVS 396
            .:.|.:.....|.:|.|  ||:|.::.|:...         .|| ::||           :.:::
Zfish    67 VVTLQIQAAYMICENEFIGKYVPSVVSLEFQS---------MFADNIGD-----------LSVIN 111

  Fly   397 STIFKNTV-LEGLDLSGNPY--LSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKNLQVLG 458
            ..:...|: ||.:||:..|.  :.::.:......|....|..:.::|..|||   |:|.:|.::.
Zfish   112 QLVHLKTLKLENIDLTNQPNTGIMFHNLTKLEKMILMNCKIFFLDKSVTKDL---KALTSLVLIP 173

  Fly   459 LAGNNI--NALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNEMLK 521
            ....||  |.:...........:.|||..:....|..|...:|..:.|         ::||..::
Zfish   174 KEAVNIIQNFMEQPTHLKYLHFQCLDLYCSCDNTWLVSWIRDNGKVEV---------VMSNPSME 229

  Fly   522 DFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLNYSQNAVGEEVISLAESLIIDRK 586
            |                   ||.:.:                        :||
Zfish   230 D-------------------LRCLTD------------------------DEV------------ 239

  Fly   587 LWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLDGDLTLKFQLLDY 651
                        .:.|...:.:.|..|.|     |::...||
Zfish   240 ------------DHLNFISYAKENCSIDL-----DFVFFSCS----------------------- 264

  Fly   652 EASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIAVMGSLVGACILGFIIYLKRWHIH 716
              |.:.|.                             ..|:.:|...||.       |.|.:
Zfish   265 --SVFLCI-----------------------------FIVVVLMYKFVGQ-------YFKPF--- 288

  Fly   717 YYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQNDRTWVLNELLPNVEETGD--V 779
            |:.:|......|....|:...             ||.|:||...|..||:.|||||:|:.|.  :
Zfish   289 YHIASGWFREALRMKEKQQYR-------------YDAFVSYSGKDEHWVIEELLPNLEQRGPPFL 340

  Fly   780 SICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFEMYLAQHRIFEVSKEHLILV 844
            .:|||.||||:|..|::||...:..|...:.::|..:|.|:||..||.||.:|:....::.||||
Zfish   341 RLCLHSRDFQLGHDIVENITDSIYASRRTLCLVSRNYLNSNWCSVEMQLATYRLQVEHRDILILV 405

  Fly   845 FLEDIPRR--KRPKTLQYLMDVKTYIKWPTAKEDRKLFWKRL 884
            |||.||.|  .....|..|:..:||:.||...|..:.||.||
Zfish   406 FLETIPSRLLSSHHRLARLVKTRTYLDWPQEPEMHEAFWDRL 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	55/274 (20%)
		leucine-rich repeat	264..287	CDD:275380	4/16 (25%)
		leucine-rich repeat	288..311	CDD:275380	3/22 (14%)
		leucine-rich repeat	312..356	CDD:275380	12/45 (27%)
		leucine-rich repeat	357..381	CDD:275380	4/24 (17%)
		leucine-rich repeat	382..397	CDD:275380	0/14 (0%)
		leucine-rich repeat	405..430	CDD:275380	6/26 (23%)
		leucine-rich repeat	432..453	CDD:275380	7/20 (35%)
		leucine-rich repeat	454..477	CDD:275380	4/24 (17%)
		leucine-rich repeat	478..501	CDD:275380	6/22 (27%)
		leucine-rich repeat	502..525	CDD:275380	4/22 (18%)
		TIR	751..891	CDD:214587	58/138 (42%)
tlr20.4	XP_073768827.1	None