DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_114470.1	Gene:	Pnliprp1 / 84028	RGDID:	620792	Length:	473	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	94/382 - (24%)
Similarity:	141/382 - (36%)	Gaps:	118/382 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VILLRLGAL--GDIAVDEEGRLTRSWWDAVPRLLTDIATIKANILTAAPLELASNIIDAVCSSTL 70
            |.|..|||.  .::..|..|..:    ||.|...|.|..:|  :|..:|.::.:..:       |
  Rat     7 VSLFLLGAAQGKEVCYDNLGCFS----DAEPWAGTAIRPLK--LLPWSPEKINTRFL-------L 58

  Fly    71 FMDRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSA 135
            :.:..|..         ||.:    ..|.||...:     |.|...||...:..|:.:...|:..
  Rat    59 YTNENPTA---------FQTL----QLSDPLTIGA-----SNFQVARKTRFIIHGFIDKGEENWV 105

  Fly   136 ISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIE---LTPLRNIHLI 197
            :.|....|... :||.:.||......|.|..:|.|..::|..:...:..|::   .:|.: :|||
  Rat   106 VDMCKNMFQVE-EVNCICVDWKKGSQTTYTQAANNVRVVGAQVAQMIDILVKNYSYSPSK-VHLI 168

  Fly   198 GGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGL 262
                               |||||||:.|.||   .:..|  :.|||||||.:..|........|
  Rat   169 -------------------GHSLGAHVAGEAG---SRTPG--LGRITGLDPVEANFEGTPEEVRL 209

  Fly   263 TRGDAKLVDIIHTNIGILAKRGPL------------GDVDFYPGGAHPIQPGCLT---------- 305
            ...||..||:|||:      ..||            |.:||:|.|...: |||..
  Rat   210 DPSDADFVDVIHTD------AAPLIPFLGFGTNQMSGHLDFFPNGGQSM-PGCKKNALSQIVDID 267

  Fly   306 ---------IGCSHTRAVEYFAES--------AYPHQEKNFMGKKCASWDELRKRDC 345
                     :.|:|.|:.:|:.||        |||          |||:.:.....|
  Rat   268 GIWSGTRDFVACNHLRSYKYYLESILNPDGFAAYP----------CASYKDFESNKC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	77/303 (25%)
Pnliprp1	NP_114470.1	Lipase	18..353	CDD:395099	89/371 (24%)
Pnliprp1	NP_114470.1	PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339034
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840