DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	332	Identity:	95/332 - (28%)
Similarity:	138/332 - (41%)	Gaps:	74/332 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 DAVCSSTLFMDR-------IPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVV 120
            ||..|.||  ||       .||||  :.|.:.:....| .||.:...:||.: ::|.|...||..
Mouse    30 DAPWSGTL--DRPLKALPWSPAQI--NTRFLLYTNENP-DNYQLITSDASNI-RNSNFRTNRKTR 88

  Fly   121 ILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHL 185
            |:..|:.:...|:....|....|... .||.:.||......|.|..:..|..::|..:.: |.::
Mouse    89 IIIHGFIDKGEENWLSDMCKNMFRVE-SVNCICVDWKGGSRTTYTQATQNVRVVGAEVAL-LVNV 151

  Fly   186 IELT---PLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAG-RTFKKLTGKLIPRITGL 246
            ::..   .|.|:|||                   |||||:||.|.|| |||     ..|.|||||
Mouse   152 LQSDLGYSLNNVHLI-------------------GHSLGSHIAGEAGKRTF-----GAIGRITGL 192

  Fly   247 DPAKPCFRREKILPGLTRGDAKLVDIIHTNIG-ILAKRG-----PLGDVDFYPGGAHPIQPGCLT 305
            |||:|.|:.......|...||:.||.|||:.| |:...|     .:|.:||:|.|...: |||..
Mouse   193 DPAEPYFQGTPEEVRLDPTDAQFVDAIHTDAGPIIPNLGFGMSQTVGHLDFFPNGGIEM-PGCQK 256

  Fly   306 -------------------IGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKR---DCSAG 348
                               ..|:|.|:.:::.:|..  ....|.|..|:|:......   .|.:|
Mouse   257 NILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIV--NPTGFAGFSCSSYSLFTANKCFPCGSG 319

  Fly   349 IVSPMGY 355
            ....||:
Mouse   320 GCPQMGH 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	83/303 (27%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	95/332 (29%)
		Pancreat_lipase_like	51..348	CDD:238363	85/309 (28%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840