DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and PNLIPRP1

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001290064.1	Gene:	PNLIPRP1 / 5407	HGNCID:	9156	Length:	467	Species:	Homo sapiens

Alignment Length:	275	Identity:	78/275 - (28%)
Similarity:	109/275 - (39%)	Gaps:	62/275 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 NYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYV 160
            |:.:.||......:.|.|...||...:..|:.:..:||....|..|.|... :||.:.||.....
Human    66 NFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVE-EVNCICVDWKKGS 129

  Fly   161 DTFYAWSALNTDLIGEHIGVGLTHLI-ELT-PLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAH 223
            ...|..:|.|..::|..:...|..|: |.: |...:|||                   |||||||
Human   130 QATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLI-------------------GHSLGAH 175

  Fly   224 IMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTNIGIL------AK 282
            :.|.||   .|..|  :.|||||||.:..|........|...||..||:|||:...|      ..
Human   176 VAGEAG---SKTPG--LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGT 235

  Fly   283 RGPLGDVDFYPGGAHPIQPGCLT-------------------IGCSHTRAVEYFAES-------- 320
            ...:|.:||:|.|...: |||..                   :.|:|.|:.:|:.||
Human   236 NQQMGHLDFFPNGGESM-PGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFA 299

  Fly   321 AYP-HQEKNFMGKKC 334
            ||| ...|:|...||
Human   300 AYPCTSYKSFESDKC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	78/275 (28%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	78/275 (28%)
		Pancreat_lipase_like	52..349	CDD:238363	78/275 (28%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145357
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840