DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Lipg

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	85/302 - (28%)
Similarity:	122/302 - (40%)	Gaps:	59/302 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 SKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCR-GDVNFVIVDAADYVDTFYAWSA 168
            |||.::..|:...|...:..|||.:....|.:..:..|...| .:.|.|:||........|..:.
  Rat    73 SKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANVVVVDWLPLAHQLYIDAV 137

  Fly   169 LNTDLIGEHIGVGLTHLIEL--TPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRT 231
            .||.::|..:...|..|.|.  ..|.::|||                   |:|||||:.|.||..
  Rat   138 SNTRVVGRRVAGMLNWLQEKGEFSLGDVHLI-------------------GYSLGAHVAGYAGNF 183

  Fly   232 FKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHT-------NIGILAKRGPLGDV 289
            .|...|    ||||||||.|.|....|...|:..||..||::||       :|||   |.|:|.:
  Rat   184 VKGTVG----RITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGI---RMPVGHI 241

  Fly   290 DFYPGGAHPIQPGC---------------LTIGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDE 339
            |.||.|. ..||||               ..:.|.|.|||..|.:|.. :|:|.....:|...:.
  Rat   242 DIYPNGG-DFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLV-NQDKPSFAFQCTDPNR 304

  Fly   340 LRK---RDCSAGIVSPMGY---RMNPQARGIYYVDVNGWPPY 375
            .::   ..|.....:.:||   :|..:.....|:......|:
  Rat   305 FKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	84/295 (28%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	84/296 (28%)
		lipo_lipase	53..488	CDD:132274	85/302 (28%)
		Heparin-binding. /evidence=ECO:0000250	327..339		2/11 (18%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338941
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940