DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_037293.2	Gene:	Pnlip / 25702	RGDID:	3360	Length:	465	Species:	Rattus norvegicus

Alignment Length:	342	Identity:	93/342 - (27%)
Similarity:	134/342 - (39%)	Gaps:	78/342 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 DAVCSSTLFMDRIPAQITP----DIRKMHFQYMTPCQ-NYSVPLLEASKLWKHSRFSKGRKVVIL 122
            ||..|.|:  || |.:..|    .|......|....| ||.....:||.: ::|.|...||..|:
  Rat    30 DAPWSGTI--DR-PLKALPWSPAQINTRFLLYTNENQDNYQKITSDASSI-RNSNFKTNRKTRII 90

  Fly   123 ATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIE 187
            ..|:.:...|:....|....|... .||.:.||........|..:..|..::|..:.: |.::::
  Rat    91 IHGFIDKGEENWLSDMCKNMFKVE-SVNCICVDWKGGSRATYTQATQNVRVVGAEVAL-LVNVLK 153

  Fly   188 ----LTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAG-RTFKKLTGKLIPRITGLD 247
                .:| .|:|||                   |||||:|:.|.|| |||     ..|.||||||
  Rat   154 SDLGYSP-DNVHLI-------------------GHSLGSHVAGEAGKRTF-----GAIGRITGLD 193

  Fly   248 PAKPCFRREKILPGLTRGDAKLVDIIHT-------NIGILAKRGPLGDVDFYPGGAHPIQPGCLT 305
            .|:|.|:.......|...||:.||.|||       |:| ......:|.:||:|.|...: |||..
  Rat   194 AAEPYFQGTPEEVRLDPTDAQFVDAIHTDAAPIIPNLG-FGMSQTVGHLDFFPNGGMEM-PGCQK 256

  Fly   306 -------------------IGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDCSAGIVS 351
                               ..|:|.|:.:|:.:|..  ....|.|..|:|::......|     .
  Rat   257 NILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIV--NPTGFSGFSCSSYNVFSANKC-----F 314

  Fly   352 PMGYRMNPQARGIYYVD 368
            |.|....||..  :|.|
  Rat   315 PCGSEGCPQMG--HYAD 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	84/316 (27%)
Pnlip	NP_037293.2	Lipase	17..352	CDD:395099	93/342 (27%)
Pnlip	NP_037293.2	PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840