DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Lipc

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_006243421.1	Gene:	Lipc / 24538	RGDID:	3009	Length:	510	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	93/356 - (26%)
Similarity:	132/356 - (37%)	Gaps:	101/356 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 DRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTN----TVNES 133
            ||:..|:.|    .|.:.:..|                 .|:....:|::..||:.    ||.:.
  Rat    59 DRLGCQLRP----QHPETLQEC-----------------GFNSSHPLVMIIHGWSGSESATVGKD 102

  Fly   134 SA------------ISMISKAFMCRGD--VNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTH 184
            |.            |..|..|...|..  ||..:||........||.:..||.::|:.:...|..
  Rat   103 SDNDSQVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLW 167

  Fly   185 LIELTPL--RNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGK-LIPRITGL 246
            |.|....  ..:|||                   |:|||||:.|.||   ..:.|| .|.|||||
  Rat   168 LEESMKFSRSKVHLI-------------------GYSLGAHVSGFAG---SSMGGKRKIGRITGL 210

  Fly   247 DPAKPCFRREKILPGLTRGDAKLVDIIHT--------NIGILAKRGPLGDVDFYPGGAHPIQPGC 303
            |||.|.|........|:..||..||.|||        ::||   :.|:...||||.|. ..||||
  Rat   211 DPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGI---KQPIAHYDFYPNGG-SFQPGC 271

  Fly   304 ------------------LTIGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRK---RDCSA 347
                              .||.|:|.|:|..|.:| ..|......|.:|::.|...:   .:|..
  Rat   272 HFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDS-LQHSNLQNTGFQCSNMDSFSQGLCLNCKK 335

  Fly   348 GIVSPMGY---RMNPQARGIYYVDVNGWPPY 375
            |..:.:||   |..|:.....::......|:
  Rat   336 GRCNSLGYDIRRDRPRKSKTLFLITRAQSPF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	88/337 (26%)
Lipc	XP_006243421.1	Lipase	18..366	CDD:278576	92/354 (26%)
		Pancreat_lipase_like	47..362	CDD:238363	92/350 (26%)
		PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940