DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5665 and Lipg

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	333	Identity:	95/333 - (28%)
Similarity:	135/333 - (40%)	Gaps:	61/333 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 IPAQITPDIRKMHFQYMT---PCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWT-NTVNESSA 135
            :||...|.:.   |...|   |.|......|..|||.::..|:...|...:..||| :.:.||..
Mouse    41 VPATARPSVA---FNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWL 102

  Fly   136 ISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIELTPLRNIHLIGGF 200
            ..::|...|...|.|.|:||........|..:..||.::|:.:...|..|.|
Mouse   103 HKLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQE------------- 154

  Fly   201 IKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRG 265
             ||.|   :.|:...:|:|||||:.|.||...|...|    ||||||||.|.|....|...|:..
Mouse   155 -KEEF---SLGNVHLIGYSLGAHVAGYAGNFVKGTVG----RITGLDPAGPMFEGVDINRRLSPD 211

  Fly   266 DAKLVDIIHT-------NIGILAKRGPLGDVDFYPGGAHPIQPGC---------------LTIGC 308
            ||..||::||       :|||   |.|:|.:|.||.|. ..||||               ..:.|
Mouse   212 DADFVDVLHTYTLSFGLSIGI---RMPVGHIDIYPNGG-DFQPGCGFNDVIGSFAYGTISEMVKC 272

  Fly   309 SHTRAVEYFAESAYPHQEKNFMGKKCASWDELRK---RDCSAGIVSPMGY---RMNPQARGIYYV 367
            .|.|||..|.:|.. :|:|.....:|......::   ..|.....:.:||   :|..:.....|:
Mouse   273 EHERAVHLFVDSLV-NQDKPSFAFQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYL 336

  Fly   368 DVNGWPPY 375
            ......|:
Mouse   337 KTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	91/316 (29%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	91/319 (29%)
		lipo_lipase	51..485	CDD:132274	92/320 (29%)
		Heparin-binding. /evidence=ECO:0000250	325..337		2/11 (18%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940