DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Lipc

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_006510879.1	Gene:	Lipc / 15450	MGIID:	96216	Length:	526	Species:	Mus musculus

Alignment Length:	341	Identity:	88/341 - (25%)
Similarity:	128/341 - (37%)	Gaps:	98/341 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 DRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTN----TVNES 133
            ||:..::.|    .|.:.:..|                 .|:..:.::::..||:.    ||.:.
Mouse    59 DRLGCRLRP----QHPETLQEC-----------------GFNSSQPLIMIIHGWSGSESATVGKD 102

  Fly   134 SA------------ISMISKAFMCRGD--VNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTH 184
            |.            |..|..|...|..  ||..:||........|..:..||.::|:.:...|..
Mouse   103 SDSDYQVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLW 167

  Fly   185 LIELTPL--RNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGK-LIPRITGL 246
            |.|....  ..:|||                   |:|||||:.|.||   ..:.|| .|.|||||
Mouse   168 LEESAKFSRSKVHLI-------------------GYSLGAHVSGFAG---SSMDGKNKIGRITGL 210

  Fly   247 DPAKPCFRREKILPGLTRGDAKLVDIIHT--------NIGILAKRGPLGDVDFYPGGAHPIQPGC 303
            |||.|.|........|:..||..||.|||        ::||   :.|:...||||.|. ..||||
Mouse   211 DPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGI---KQPIAHYDFYPNGG-SFQPGC 271

  Fly   304 ------------------LTIGCSHTRAVEYFAESAYPHQEKNFMGKKCA---SWDELRKRDCSA 347
                              .||.|:|.|:|..|.:| ..|.:...:|.:|:   |:.:.....|..
Mouse   272 HFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDS-LQHSDLQSIGFQCSDMGSFSQGLCLSCKK 335

  Fly   348 GIVSPMGYRMNPQARG 363
            |..:.:||.:.....|
Mouse   336 GRCNTLGYDIRKDRSG 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	85/329 (26%)
Lipc	XP_006510879.1	Lipase	18..366	CDD:333880	88/341 (26%)
Lipc	XP_006510879.1	PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840