DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and AgaP_AGAP004449

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_313740.5	Gene:	AgaP_AGAP004449 / 1274594	VectorBaseID:	AGAP004449	Length:	393	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	87/289 - (30%)
Similarity:	121/289 - (41%)	Gaps:	40/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTF 163
            ||.:::.   :.|.|:..|...::..|:.| ...|.....:..|.:...|||.:.:|.:|.....
Mosquito   134 VPTVQSV---ESSFFNDSRPTRVIVHGFCN-CQHSDFCQSVKDALLYANDVNIISIDWSDTAGLL 194

  Fly   164 -YAWSALNTDLIGEHIG--VGLTHLIELTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIM 225
             |....|..|.:...:.  |...|......|..:||                   ||||||||:.
Mosquito   195 DYILLRLRLDQVAASLAGFVDFLHNTTNLDLSQLHL-------------------VGHSLGAHLA 240

  Fly   226 GTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTNIGILAKRGPLGDVD 290
            |.:|   |::|...:..|.|||||.|.|........|...||..|::||||.|.|....|:|..|
Mosquito   241 GLSG---KRVTSGRVGAIIGLDPAGPLFSSRDPKSRLDGTDAAYVEVIHTNGGTLGMYDPIGTAD 302

  Fly   291 FYP-GGAHPIQPGCLT----IGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDCSAGI- 349
            ||| ||.|  |||||.    :.|||.||.|.:|||.|  ....|....|.:..::....|...:
Mosquito   303 FYPNGGKH--QPGCLPWIFGMSCSHGRAWELYAESVY--TPVGFKAVPCDTVQQIEGSVCRIDLP 363

  Fly   350 -VSPMGYRMNPQARGIYYVDVNGWPPYGR 377
             |...|..:|....|::.:..|...||.|
Mosquito   364 TVDMGGEPVNKTKSGLFVLSTNSRFPYAR 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	83/280 (30%)
AgaP_AGAP004449	XP_313740.5	Pancreat_lipase_like	116..386	CDD:238363	83/281 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810