DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_476554.1	Gene:	Pnliprp2 / 117554	RGDID:	620793	Length:	482	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	88/314 - (28%)
Similarity:	133/314 - (42%)	Gaps:	83/314 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 PAQITP------DIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESS 134
            |.:|.|      |.|.:.:....|.....:...|...: |.|.|...||...:..|:.:...:..
  Rat    54 PLKIFPWSPEDIDTRFLLYTNENPNNYQKISATEPDTI-KFSNFQLDRKTRFIVHGFIDKGEDGW 117

  Fly   135 AISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIEL-------TPLR 192
            .:.|..|.|... .||.:.||......|.|..::.||.::|..|    ..|:::       :| .
  Rat   118 LLDMCKKMFQVE-KVNCICVDWRRGSRTEYTQASYNTRVVGAEI----AFLVQVLSTEMGYSP-E 176

  Fly   193 NIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREK 257
            |:|||                   |||||||::|.|||   :|.|. :.||||||||:|||:.
  Rat   177 NVHLI-------------------GHSLGAHVVGEAGR---RLEGH-VGRITGLDPAEPCFQG-- 216

  Fly   258 ILPGLTR---GDAKLVDIIHTN---------IGILAKRGPLGDVDFYPGGAHPIQPGCLT----- 305
             ||...|   .||..||:|||:         .|:..|   :|.:||:|.|...: |||..
  Rat   217 -LPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQK---VGHLDFFPNGGKEM-PGCQKNILST 276

  Fly   306 --------------IGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDC 345
                          :.|:|.|:.:|:|.|..  ....|:|..|:|:::.::.||
  Rat   277 IVDINGIWEGTQNFVACNHLRSYKYYASSIL--NPDGFLGYPCSSYEKFQQNDC 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	83/299 (28%)
Pnliprp2	NP_476554.1	Lipase	31..367	CDD:278576	88/314 (28%)
		Pancreat_lipase_like	65..363	CDD:238363	85/303 (28%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339037
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840