DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5665 and pnlip

DIOPT Version :9

Sequence 1:	NP_001246844.1	Gene:	CG5665 / 40243	FlyBaseID:	FBgn0036977	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_031760687.1	Gene:	pnlip / 100145526	XenbaseID:	XB-GENE-6054594	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	365	Identity:	90/365 - (24%)
Similarity:	139/365 - (38%)	Gaps:	93/365 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 VCSSTL--FMDRIPAQITPD--------------IRKMHFQYMTPCQNYSVPLLEASKLWKHSRF 113
            ||.:.:  |.|.:|...|.:              .|.:.|....|.....:..:..|.: ..|.|
Frog    20 VCYNRIGCFPDSVPWAGTVERPINHLPQSPEKINTRFLLFTQQNPNSYQEISAINPSTI-SASNF 83

  Fly   114 SKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHI 178
            ...||...:..|:.:. .|.|.::.:.|..:...|||.:.||......|.|..:|.|..::|..:
Frog    84 RTNRKTRFIIHGFIDK-GEESWLTDMCKTMLQVEDVNCLCVDWMGGSRTLYTQAANNIRVVGAEV 147

  Fly   179 GV---GLTHLIELTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLI 240
            ..   .||.:...:|.. :|:|                   ||||||...|.||:..|.     |
Frog   148 AYFIDTLTSMYGHSPAM-VHVI-------------------GHSLGAQAAGEAGKRRKG-----I 187

  Fly   241 PRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTN-IGILAKRG-----PLGDVDFYPGGAHPI 299
            .||||||||:|.|:...|...|...|||.||:|||: ..::...|     .:|.:||:|.|...:
Frog   188 GRITGLDPAEPYFQGTPIEVRLDPSDAKFVDVIHTDAASVIPYLGFGTSQLVGHLDFFPNGGEQM 252

  Fly   300 QPGCLT-------------------IGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDC 345
             |||..                   :.|:|.|:.:|:..|..  :...|:|...:::|..:
Frog   253 -PGCKKNVLSQIVDLDGIWQGTRDFVACNHLRSYKYYTNSIL--KRDGFVGFPSSTYDTFK---- 310

  Fly   346 SAGIVSPMGYRMNPQARGIYYVDVNGWPPYGRNSENTVDP 385
             :|.|.|.     |.         .|.|..|..::|...|
Frog   311 -SGAVFPC-----PS---------GGCPLMGHYADNYTGP 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5665	NP_001246844.1	Abhydrolase	85..370	CDD:304388	78/312 (25%)
pnlip	XP_031760687.1	Lipase	18..352	CDD:395099	90/365 (25%)
pnlip	XP_031760687.1	PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100