DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kin17 and RTS2

DIOPT Version :9

Sequence 1:	NP_649212.2	Gene:	kin17 / 40242	FlyBaseID:	FBgn0024887	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_014720.1	Gene:	RTS2 / 854244	SGDID:	S000005603	Length:	232	Species:	Saccharomyces cerevisiae

Alignment Length:	253	Identity:	71/253 - (28%)
Similarity:	126/253 - (49%)	Gaps:	43/253 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFLHSF 68
            |:..:.||.:.:...:||||.|:|||:|::||:|.|||:.|..|.||.|::   :....:....:
Yeast     2 ADYDSAKYWSKQGARRGLQKTRYYCQICQRQCKDANGFQSHNKSPSHLRKI---SQVTAEDARRY 63

  Fly    69 SKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIAD-- 131
            :.:|..|:::||::|.|.|...|||:|.||:..::|:|||||...:|:.:|::|||.|:|..|
Yeast    64 NIQFEKGFLQLLKQRHGEKWIDANKVYNEYVQDRDHVHMNATMHRSLTQFVRYLGRAGKVDVDMD 128

  Fly   132 -----ETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEEDEGQ 191
                 |..:|..:..|  .|.::...::.......:::.|...|:.:::|:..||.
Yeast   129 IDDTSENVEGPLLIRI--HPSSLSSPSEDGMLRSQQEEQEVIAAELLKRQLNRAKR--------- 182

  Fly   192 EKFTELKREENEPLKLDIRLEKKFQPD---TVLGKSALAK-RPAPEAEEKVFKKPKSV 245
                              :.||.:||:   .:.|.|.|.: :.......:|.||.|.|
Yeast   183 ------------------QTEKVYQPEMKSEISGDSTLKRVQVTFHGNGRVNKKKKKV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kin17	NP_649212.2	Kin17_mid	55..177	CDD:287344	33/128 (26%)
kin17	NP_649212.2	KOW_KIN17	336..387	CDD:240519
RTS2	NP_014720.1	ZnF_U1	21..55	CDD:197732	17/36 (47%)
RTS2	NP_014720.1	Kin17_mid	50..>137	CDD:402119	29/89 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346558
Domainoid	1	1.000	68	1.000	Domainoid score	I2319
eggNOG	1	0.900	-	-		E1_KOG2837
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1345
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004270
OrthoInspector	1	1.000	-	-		oto99275
orthoMCL	1	0.900	-	-		OOG6_102520
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R638
SonicParanoid	1	1.000	-	-		X3008
TreeFam	0	0.000	Not matched by this tool.
	11	10.620