DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kin17 and kin

DIOPT Version :9

Sequence 1:	NP_649212.2	Gene:	kin17 / 40242	FlyBaseID:	FBgn0024887	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001004824.1	Gene:	kin / 448079	XenbaseID:	XB-GENE-980671	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	407	Identity:	200/407 - (49%)
Similarity:	274/407 - (67%)	Gaps:	39/407 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFL 65
            ||:|:..|||.:||::|||||||||||||||:||||||||||||.|||||||||||.::||.:|:
Frog     1 MGKADFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFM 65

  Fly    66 HSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIA 130
            ..||.||...::|||||||||||...|.:|.|||:|:||:|||||:|.||:|:.|||||.|....
Frog    66 DYFSDEFRTEFLELLRRRFGTKRVHNNIVYNEYISHREHVHMNATQWETLTDFTKWLGRAGYCKV 130

  Fly   131 DETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEE--DEGQEK 193
            |||.|||::.||||.||.:.:|.:.::|:|.:.|||||.|.|||:|:|.     |.|  ::....
Frog   131 DETPKGWYIQYIDRDPETIRKQQEQEKKKKQDLDDEERTAKFIEEQVKK-----GLEVTEQNTPT 190

  Fly   194 FTELKREENEPLKLDIRLEK------------------KFQPDTVLGKSALAKRPAPEAEEKVFK 240
            :|||.| :||..|:...|.|                  ..:...|:|  ::.::...:.:.|..|
Frog   191 YTELSR-QNEEEKVAFNLNKGASTSGTATTKSSSLVSNALKSAAVMG--SVKRKDTSQVQPKEKK 252

  Fly   241 KPKSVAGDSQTRSVLDEIIKQEESKKERANRKDYWLHKGIVVKFISKSMGEKFFKQKAVVLDVID 305
            |          :|.||||::.|| ||::..|.|:||...||||.::|.:|||::|:||||.:|||
Frog   253 K----------KSALDEIMEMEE-KKKKTERTDFWLQPEIVVKIVTKKLGEKYYKKKAVVKEVID 306

  Fly   306 RYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEILHGP 370
            ||...:|.:::|:|||:||.||||||||..|.|.|:||.|:|...:|..::|:.:|.::||..||
Frog   307 RYTAVVKLVDSGDKLKLDQTHLETVIPAPGKRVFVLNGGYKGHFGILDCINEKSFSATIEIDSGP 371

  Fly   371 LKGRIVDNVQYEDISKL 387
            ||||.|:.:.||||||:
Frog   372 LKGRKVEGIPYEDISKV 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kin17	NP_649212.2	Kin17_mid	55..177	CDD:287344	67/121 (55%)
kin17	NP_649212.2	KOW_KIN17	336..387	CDD:240519	24/50 (48%)
kin	NP_001004824.1	Kin17_mid	55..177	CDD:313562	67/121 (55%)
kin	NP_001004824.1	KOW_KIN17	335..388	CDD:240519	24/52 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5570
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8196
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2085
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1420569at2759
OrthoFinder	1	1.000	-	-		FOG0004270
OrthoInspector	1	1.000	-	-		oto103012
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3008
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060