DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kin17 and SPBC365.09c

DIOPT Version :9

Sequence 1:	NP_649212.2	Gene:	kin17 / 40242	FlyBaseID:	FBgn0024887	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_596038.1	Gene:	SPBC365.09c / 2540949	PomBaseID:	SPBC365.09c	Length:	304	Species:	Schizosaccharomyces pombe

Alignment Length:	314	Identity:	119/314 - (37%)
Similarity:	175/314 - (55%)	Gaps:	53/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFL 65
            |||||.||||.::|.:||||||:|||||..|:||.||||||||||.||.|.||:.:.|.||||.:
pombe     1 MGRAEAGTPKAISNALKSKGLQRLRWYCSACQKQMRDENGFKCHTQSEGHIRQMNVIAMNPGKRI 65

  Fly    66 HSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIA 130
            ..||.:|...::.|||...|.|:...|:.|||||..|.|:|||||||.|||::.|:|||.|....
pombe    66 QDFSNQFLRDFISLLRTAHGEKKIHFNQFYQEYIRDKNHVHMNATRWHTLSEFCKFLGRQGMCRV 130

  Fly   131 DETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNA--KAKDGEED-EGQE 192
            :|.|||:|::|||::|..:.|.....::|:.||.|||:....:::|||.|  .|::.|:: :|..
pombe   131 EENEKGFFISYIDKNPANILRNEANKKRERQEKSDEEQRLRLLDEQIKRAYESAQNNEDNKDGSS 195

  Fly   193 KFTELKREENEPLKLDIRLEKKFQPDTVLGKSALAKRPAPEAEEKVFK----------------- 240
            :        .:|:..:|.|.||..|   :..:..:...:..|:.:.|:
pombe   196 R--------EQPVLHEIDLSKKGNP---IQLNLSSSSDSHSAQNEFFQTRNTPTFSFSSSSSQTS 249

  Fly   241 ---KPKSVAGD-------------------SQTRSVLDEIIKQEESKKERANRK 272
               |||:|..:                   .:.||.:::||.||..:::|.|.|
pombe   250 LKHKPKNVFAELNKSRKKNNKDSLDQGQNVKRPRSAVEDIIAQETMREKRRNIK 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kin17	NP_649212.2	Kin17_mid	55..177	CDD:287344	52/121 (43%)
kin17	NP_649212.2	KOW_KIN17	336..387	CDD:240519
SPBC365.09c	NP_596038.1	Kin17_mid	56..177	CDD:287344	52/120 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1454
eggNOG	1	0.900	-	-		E1_KOG2837
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	212	1.000	Inparanoid score	I941
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004270
OrthoInspector	1	1.000	-	-		oto100844
orthoMCL	1	0.900	-	-		OOG6_102520
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R638
SonicParanoid	1	1.000	-	-		X3008
TreeFam	1	0.960	-	-
	11	10.750