Protein Alignment kin17 and KIN

DIOPT Version :9

• Sequence 1: NP_649212.2
• Gene: kin17 / 40242
• FlyBaseID: FBgn0024887
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_006717497.1
• Gene: KIN / 22944
• HGNCID: 6327
• Length: 394
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 192/387 - (49%)
• Similarity: 263/387 - (67%)
• Gaps: 37/387 - (9%)

  Fly     1 MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFL 65
            ||:::..|||.:||::|||||||||||||||:||||||||||||.|||||||||||.::||.:|:
Human     1 MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFM 65

  Fly    66 HSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIA 130
            ..||:||.:.::|||||||||||...|.:|.|||:|:||||||||:|.||:|:.|||||.|....
Human    66 DYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKV 130

  Fly   131 DETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEEDEGQEKFT 195
            |||.|||::.||||.||.:.||.:.::|:|.:.||||:.|.|||:|::  :..:|:|.| ...||
Human   131 DETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKEQE-VPTFT 192

  Fly   196 ELKREENEPLKLDIRLEK--------KFQPDTVLGKSAL-------------AKRPAPEAEEKVF 239
            ||.||.:|. |:...|.|        .....:.||.|||             :.:.:.:::||..
Human   193 ELSRENDEE-KVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKK 256

  Fly   240 KKPKSVAGDSQTRSVLDEIIKQEESKKERANRKDYWLHKGIVVKFISKSMGEKFFKQKAVVLDVI 304
            ||           |.||||::.||.|| |..|.||||...|:||.|:|.:|||:.|:||:|.:||
Human   257 KK-----------SALDEIMEIEEEKK-RTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVI 309

  Fly   305 DRYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEI 366
            |:|...:|.:::|:|||:||.||||||||..|.::|:||.|||:|..|..::|:.:|.::.|
Human   310 DKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVI 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kin17	NP_649212.2	Kin17_mid	55..177	CDD:287344	68/121 (56%)
		KOW_KIN17	336..387	CDD:240519	12/31 (39%)
KIN	XP_006717497.1	Kin17_mid	55..177	CDD:287344	68/121 (56%)
		KOW	339..>373	CDD:294253	12/33 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159821
Domainoid	1	1.000	164	1.000	Domainoid score	I3953
eggNOG	1	0.900	-	-		E1_KOG2837
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8196
Inparanoid	1	1.050	405	1.000	Inparanoid score	I1909
Isobase	1	0.950	-	0	Normalized mean entropy	S1345
OMA	1	1.010	-	-		QHG54826
OrthoDB	1	1.010	-	-		D1420569at2759
OrthoFinder	1	1.000	-	-		FOG0004270
OrthoInspector	1	1.000	-	-		oto89163
orthoMCL	1	0.900	-	-		OOG6_102520
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R638
SonicParanoid	1	1.000	-	-		X3008
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.650