Protein Alignment CG5618 and SGPL1

DIOPT Version :9

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_003892.2
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 568
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 92/447 - (20%)
• Similarity: 145/447 - (32%)
• Gaps: 144/447 - (32%)

  Fly    22 W-KILENVFHLLRK--------EDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETENCSLAE 77
            | :..:..|.|.||        :|.  ::..|.|..|.:.||:.|  ||.:  |...::..|.:.
Human    67 WSRFKKKCFKLTRKMPIIGRKIQDK--LNKTKDDISKNMSFLKVD--KEYV--KALPSQGLSSSA 125

  Fly    78 IEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTYE--------------- 127
            :.|..::                 :..:|.|...|     ..:|:.|:.|
Human   126 VLEKLKE-----------------YSSMDAFWQEG-----RASGTVYSGEEKLTELLVKAYGDFA 168

  Fly   128 --------VAPVFSLIETEVIATICKL-AGYKEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSG 183
                    :.|....||.|::...|.| .|..:..|....||:.|.:  |....|:.....|
Human   169 WSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGGTESIL--MACKAYRDLAFEK--- 228

  Fly   184 MFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFF 248
              |::...:.....:|.:|.|||::.|:   ..|.|...   :|:..|:.|.   .:|.......
Human   229 --GIKTPEIVAPQSAHAAFNKAASYFGM---KIVRVPLT---KMMEVDVRAM---RRAISRNTAM 282

  Fly   249 VNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERA--------- 304
            :.|:......|..|.:...|.:..::.:.|||||||||         .||..:|:|
Human   283 LVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGG---------FLIVFMEKAGYPLEHPFD 338

  Fly   305 ------NSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDT------ 357
                  .|.|.:.||...||...||.|                 |..::.:.|....||
Human   339 FRVKGVTSISADTHKYGYAPKGSSLVL-----------------YSDKKYRNYQFFVDTDWQGGI 386

  Fly   358 -----------GNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKL 403
                       |..|..|         |..|...|...|.......|..||.|:.:|
Human   387 YASPTIAGSRPGGISAAC---------WAALMHFGENGYVEATKQIIKTARFLKSEL 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	75/363 (21%)
SGPL1	NP_003892.2	DOPA_deC_like	144..507	CDD:99743	72/342 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810