DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and hdc

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_005169965.1	Gene:	hdc / 793609	ZFINID:	ZDB-GENE-080102-5	Length:	608	Species:	Danio rerio

Alignment Length:	403	Identity:	97/403 - (24%)
Similarity:	178/403 - (44%)	Gaps:	55/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 KQKIVPFLQPDKLKELI-NLKVRETENCS--LAEIEELCQQ-VIHYSVKTSHGRFHNQLFGQLDP 107
            ::::||.:||..::.|: :....|.|:.|  :.::|.:... |:|:.....|.     .|..|:.
Zfish    26 ERRVVPDVQPGFMRPLLPSSAPYEPEDWSTIMQDVENIIMPGVVHWQSPHMHA-----YFPALNS 85

  Fly   108 F-GLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKE----------GDGIFAPGGS 161
            : .|.|.::.:|:|...:|:..:|..:.:|..|:..:||..|..:          |.||.....|
Zfish    86 WPSLLGDMLADAINCLGFTWASSPACTELEMCVLDWLCKALGLPDHYLHHHPQSTGGGILQSTVS 150

  Fly   162 TSNMYGMVLARYKIAPEVKT--------SGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVS 218
            ...:..::.||.....::|:        ..:...| ||.:.||::|.|..||      |..:.|.
Zfish   151 ECTLVALLAARKDRILQMKSEATHTDTDESVLNSR-LVAYASDQAHSSVEKA------GLISLVK 208

  Fly   219 VR---TNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHV 280
            :|   |:....:..:.|:..:.|.:..|..|..|..|.|:|.:.:||.::....|..|.||||||
Zfish   209 IRFLQTDAVFSLRGETLQRAVEEDRRSGLIPVMVCATLGSTGVCSFDRLDELGPVCVREGLWLHV 273

  Fly   281 DACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLF 345
            ||...|:|||..:.|..:.|::.|:||.:||.|.:.....|:.|..:         |..:....|
Zfish   274 DAAYAGSALLCPELRYFLDGIQFADSFVFNPSKWMLVHFDCTAFWVK---------NKMKLQQTF 329

  Fly   346 QQDKFYDVSYDTGNKS------VQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLR 404
            ..|..| :.:|..|.:      :...|:..:.|.|.::::.|..|....:.|.:.:|:|.|..:|
Zfish   330 TVDPLY-LRHDNSNATDFMHWQIPLSRRFRSLKLWFVIRSFGLKKLQEHIRHGVEMAKLFESLVR 393

  Fly   405 QRGDRFRLVIPEH 417
             ....|::....|
Zfish   394 -NDTHFQIPAQRH 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	85/349 (24%)
hdc	XP_005169965.1	Pyridoxal_deC	35..414	CDD:278699	94/394 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810