DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and Csad

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_068518.1	Gene:	Csad / 60356	RGDID:	621030	Length:	493	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	228/461 - (49%)
Similarity:	322/461 - (69%)	Gaps:	8/461 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 QKIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAG 112
            :|:..:.:|::||:|::|:: :::..|...|.|.|:.||||||||.|.||.||||..|||..|||
  Rat    41 EKVCEWKEPEELKQLLDLEL-QSQGESRERILERCRAVIHYSVKTGHPRFFNQLFSGLDPHALAG 104

  Fly   113 ALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAP 177
            .::||::|.|.||||:||||.|:|.||:..:..|.|:..|||:|.||||.||||.:.|||::..|
  Rat   105 RIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGWNTGDGVFCPGGSISNMYAINLARFQRYP 169

  Fly   178 EVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKAR 242
            :.|..|:..:.||.||||.|.|||..|.|.:||||:.:...|:.:|||:|:.:|||.:|:.|:|.
  Rat   170 DCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADERGKMIPEDLERQISLAEAE 234

  Fly   243 GGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERANSF 307
            |..||.|:.|:|||||||||.::..|||.:||||||||||..||:.|||..:|.|:.|::||:|.
  Rat   235 GSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWLHVDAAWGGSVLLSRTHRHLLDGIQRADSV 299

  Fly   308 SWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFK 372
            :|||||.:.|.||||..|.|::..||:||:.::|.|||||||||:|:.|||:|.|||||::|..|
  Rat   300 AWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYNVALDTGDKVVQCGRRVDCLK 364

  Fly   373 FWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEE 437
            .|||.||:|.......:|.|..:.|.|..::::| :.|.||: |.|:.||||||:|.::|  .::
  Rat   365 LWLMWKAQGGQGLEWRIDQAFALTRYLVEEIKKR-EGFELVM-EPEFVNVCFWFVPPSLR--GKK 425

  Fly   438 ETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIE 502
            |:|::..||..|||.:||:|...||:||||.|...:  .|||||| ...|||...::||:|.|:|
  Rat   426 ESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTR--ANFFRMV-VANPILVQADIDFLLGELE 487

  Fly   503 RLGEKI 508
            |||:.:
  Rat   488 RLGQDL 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	205/406 (50%)
Csad	NP_068518.1	DOPA_deC_like	89..489	CDD:99743	205/406 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	1	1.100	-	-	LDO	PTHR45677
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830