Protein Alignment CG5618 and gad2

DIOPT Version :9

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001017708.2
• Gene: gad2 / 550403
• ZFINID: ZDB-GENE-030909-9
• Length: 583
• Species: Danio rerio
• Alignment Length: 499
• Identity: 213/499 - (42%)
• Similarity: 317/499 - (63%)
• Gaps: 21/499 - (4%)

  Fly    16 DGLMDDWKILENVFHLLRKEDTFCVDPQKWDKQ-KIVPFLQPDKLKELINLKVRETENCSLAEIE 79
            ||.......|:.|..:|.   .:.|  :.:|:. |::.|..|::|.:..|.::.: |..:|.:|.
Zfish   100 DGDAKTMNFLQEVVDILL---AYIV--ESFDRSTKVIDFHYPNELLQRNNWELSD-EPETLDDIL 158

  Fly    80 ELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATIC 144
            ..|:..:.|::||:|.|:.|||...||..|||...:|...|.:.:||||||||.|:|...:..:.
Zfish   159 ISCRATLKYAIKTAHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEVAPVFVLLEYVTLKKMR 223

  Fly   145 KLAGYKE--GDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAAN 207
            ::.|:::  |||||:|||:.||||.|:|||||:.||||..||..:..||.|||:.||:|..|.|.
Zfish   224 EIIGWQDGHGDGIFSPGGAISNMYAMLLARYKMFPEVKEKGMSSVPRLVAFTSEHSHFSIKKGAA 288

  Fly   208 WLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTE 272
            .||:|:.:.:.::.:|||:|:..|||.:|.|||.:|..||||:.||||||.||||.:...||:.:
Zfish   289 ALGIGTESVICIKADERGKMIPSDLERRIIEAKQKGYVPFFVSATAGTTVYGAFDPLIAIADICK 353

  Fly   273 RHGLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCN 337
            :|.:|:|||...||:.|:|.|:|..:.|:|||||.:|||||.:..|||||..|.||.| |::.||
Zfish   354 KHDVWMHVDGAWGGSLLMSRKHRWKLNGVERANSMTWNPHKMMAVPLQCSALLVREEG-LMQSCN 417

  Fly   338 STEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGK 402
            ..:|.|||||||.||:.||||:|::||||.:|.||.|||.:|:|...:...:|..:.::..|..|
Zfish   418 QMQACYLFQQDKHYDLQYDTGDKALQCGRHVDIFKLWLMWRAKGTIGFEAQIDKCLELSEYLYNK 482

  Fly   403 LRQRGDRFRLVI---PEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLM 464
            ::.| :.:::|.   |:|  :|||||::|..:|..  |:..|...||:.|||.||.:|...||.|
Zfish   483 IKDR-EGYQMVFDGKPQH--TNVCFWYLPPGVRYL--EDKVERMKRLHKVAPVIKARMMEYGTTM 542

  Fly   465 IGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLGEKI 508
            :.|.|...|  .||||||.: .|....:::||:::||||||:.:
Zfish   543 VSYQPQGDK--VNFFRMVIS-NPAATFEDIDFLIEEIERLGQDL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	189/411 (46%)
gad2	NP_001017708.2	Pyridoxal_deC	136..506	CDD:278699	170/374 (45%)
		TIM_phosphate_binding	511..>561	CDD:304361	23/54 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730