DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and csad

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_009295318.1	Gene:	csad / 492476	ZFINID:	ZDB-GENE-041114-36	Length:	544	Species:	Danio rerio

Alignment Length:	496	Identity:	238/496 - (47%)
Similarity:	328/496 - (66%)	Gaps:	20/496 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 MD--DWKI-LENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETENCSLAEIEE 80
            ||  |.|: |...|:::.:|   .::..:..|:|:..:..||:|:.|::|::|:...|.    |:
Zfish    63 MDESDGKLFLTEAFNIIMEE---ILNKGRDLKEKVCEWKDPDQLRSLLDLELRDHGECH----EK 120

  Fly    81 LCQQ---VIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTYEVAPVFSLIETEVIAT 142
            |.|:   |..|||||.|.||.||||..:|...|.|.|:||.:|.|.|||||||||.|:|.|||:.
Zfish   121 LLQRVRDVAKYSVKTCHPRFFNQLFAGVDYHALTGRLITETLNTSQYTYEVAPVFVLMEEEVISK 185

  Fly   143 ICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAAN 207
            :..|.|:.||||||.||||.||||.:.:|||...|:|||.|::....:.:|||.:||||..|.|.
Zfish   186 LRSLVGWSEGDGIFCPGGSMSNMYAINVARYWAFPQVKTKGLWAAPRMAIFTSQQSHYSVKKGAA 250

  Fly   208 WLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTE 272
            :||:|:.|...|:.:|.|.|:.:||||||.:||::...|||||.||||||.||||.:...||:.|
Zfish   251 FLGIGTENVFIVQVDESGSMIPEDLEAKIVQAKSQDAVPFFVNATAGTTVQGAFDPLKRIADICE 315

  Fly   273 RHGLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCN 337
            |:|:|:||||..||:.|.|.|:|.|:||:|||||.:|||||.:...||||:.|.|::..||..|:
Zfish   316 RNGMWMHVDAAWGGSVLFSKKHRHLVAGIERANSVTWNPHKMLLTGLQCSVILFRDTTNLLMHCH 380

  Fly   338 STEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGK 402
            |.:|.||||||||||.|.|||:||:|||||:|..|.|||.||.|.......||.|..:.|.|..:
Zfish   381 SAKATYLFQQDKFYDTSLDTGDKSIQCGRKVDCLKLWLMWKAIGASGLSQRVDKAFALTRYLVEE 445

  Fly   403 LRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIGY 467
            :.:| :.|:||. :..:.||||||||.:::  .:|.:|::..||..|||.|||:|...||:|:||
Zfish   446 MEKR-ENFQLVC-KGPFVNVCFWFIPPSLK--GKENSPDYQERLSKVAPVIKERMMKRGTMMVGY 506

  Fly   468 SPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLGEKI 508
            .|:...  .||||||... |.|.:|::||.|||:|:||:.:
Zfish   507 QPMDEH--VNFFRMVVVS-PQLTTKDMDFFLDEMEKLGKDL 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	209/406 (51%)
csad	XP_009295318.1	DOPA_deC_like	140..540	CDD:99743	209/406 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	1	1.100	-	-	LDO	PTHR45677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.830