DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5618 and Gadl1

DIOPT Version :9

Sequence 1:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_008764882.3	Gene:	Gadl1 / 367181	RGDID:	1565145	Length:	600	Species:	Rattus norvegicus

Alignment Length:	513	Identity:	240/513 - (46%)
Similarity:	337/513 - (65%)	Gaps:	36/513 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VDGAETVDQIRDGLMDDWK------------ILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPD 57
            |||.     :.:|...|.|            |:|.|  :|:..|.         .:|:..:..|:
  Rat   109 VDGV-----VLNGPQTDVKAGEKFVEEACRLIMEEV--VLKATDI---------NEKVCEWQPPE 157

  Fly    58 KLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGS 122
            :|::|::|::|:|.. |..::.:|||.||.|||||:|.||.|||:..||...||..::|||:|.|
  Rat   158 QLRQLLDLEMRDTGE-SQDKLLKLCQDVIRYSVKTNHPRFFNQLYAGLDYHSLAARIITEALNPS 221

  Fly   123 TYTYEVAPVFSLIETEVIATICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGM 187
            .|||||:|||.|:|..|:..:.:..|:|||||||.||||.|||..|.||||:..|::|..|:.|:
  Rat   222 IYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKDKGLSGL 286

  Fly   188 RPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKARGGEPFFVNCT 252
            ..|:||||.|.|||..|||::||:|:.|...|.|:.||:|:.::||.:|.:.|..|..||.|..|
  Rat   287 PRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEELEKQIWQGKQEGAVPFLVCAT 351

  Fly   253 AGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGA 317
            :|||||||||.::..|:|.|||||||||||..||:||:|.|:|.|:.|:.||:|.:|||||.:.|
  Rat   352 SGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMA 416

  Fly   318 PLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGY 382
            .:|||..|.::...||::|.|.:|.||||||||||||||||:||:||.|:.||||||:..||.|.
  Rat   417 GIQCSALLVKDKSDLLKKCYSAKATYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKAVGT 481

  Fly   383 GKYGLMVDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLY 447
            ......|:.|..::|.|..::::| :.|:|:| |.||:|||||:||.::|..:  |.||:|.:|.
  Rat   482 SGLEERVNRAFALSRYLVDEIKKR-EGFKLLI-EPEYTNVCFWYIPPSLREMA--EGPEFWRKLS 542

  Fly   448 TVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLG 505
            .|||.|||:|...|:||:||.|.:.|  .||||.| ...|.:..:::||:||||:.||
  Rat   543 LVAPAIKEKMMKKGSLMLGYQPHRGK--VNFFRQV-VISPQVSREDMDFLLDEIDSLG 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	207/406 (51%)
Gadl1	XP_008764882.3	DOPA_deC_like	196..596	CDD:99743	207/406 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010