Protein Alignment CG5618 and HDC

DIOPT Version :9

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_016877583.1
• Gene: HDC / 3067
• HGNCID: 4855
• Length: 697
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 99/416 - (23%)
• Similarity: 172/416 - (41%)
• Gaps: 72/416 - (17%)

  Fly    47 KQKIVPFLQPDKLKELINLKVRE---TENCSLAEIEELCQQ-VIHYSVKTSHGRFHNQLFGQLDP 107
            ::::.|.:||..|:..:.....|   :.:....:||.:... |:|:.....|.     .:..|..
Human    27 ERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDIERIIMPGVVHWQSPHMHA-----YYPALTS 86

  Fly   108 F-GLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKE----------GDGIFAPGGS 161
            : .|.|.::.:|:|...:|:..:|..:.:|..|:..:.|:.|..|          |.|:.....|
Human    87 WPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQSTVS 151

  Fly   162 TSNMYGMVLARYKIAPEVKTS------GMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVR 220
            .|.:..::.||.....|:|||      .....| ||.:.||::| |.|:.|..:.|.....:.|.
Human   152 ESTLIALLAARKNKILEMKTSEPDADESCLNAR-LVAYASDQAH-SSVEKAGLISLVKMKFLPVD 214

  Fly   221 TN--ERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERH--------- 274
            .|  .||:.    |:..|.|.|.||..|.||..|.|||.:.|||.::....:::.|
Human   215 DNFSLRGEA----LQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPISKAHHPCSPPLSL 275

  Fly   275 --------------------------GLWLHVDACLGGAALLSAKNRSLIAGLERANSFSWNPHK 313
                                      |||||:||...|.|.|..:.|..:.|:|.|:||::||.|
Human   276 ARCETSFPTSYLPSGQVMFASSGAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTFNPSK 340

  Fly   314 TIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLK 378
            .:.....|:.|..::..: |::..|....||...:.  .|:.|..:..:...|:..:.|.|.:::
Human   341 WMMVHFDCTGFWVKDKYK-LQQTFSVNPIYLRHANS--GVATDFMHWQIPLSRRFRSVKLWFVIR 402

  Fly   379 ARGYGKYGLMVDHAIHIARLLEGKLR 404
            :.|.......|.|...:|:..|..:|
Human   403 SFGVKNLQAHVRHGTEMAKYFESLVR 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	89/362 (25%)
HDC	XP_016877583.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810