Protein Alignment CG5618 and DDC

DIOPT Version :9

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_000781.2
• Gene: DDC / 1644
• HGNCID: 2719
• Length: 480
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 99/405 - (24%)
• Similarity: 179/405 - (44%)
• Gaps: 77/405 - (19%)

  Fly    55 QPDKLKELINLKVRETENCSLAEIEELCQQ-VIHYSVKTSHGRFHNQLFGQLDPFGLA-GALVTE 117
            :||..:::||            ::|::... |.|:         |:..|....|...: .|::.:
Human    49 EPDTFEDIIN------------DVEKIIMPGVTHW---------HSPYFFAYFPTASSYPAMLAD 92

  Fly   118 AMNGST----YTYEVAPVFSLIETEVIATICKL-----------AGYKEGDGIFAPGGSTSNMYG 167
            .:.|:.    :::..:|..:.:||.::..:.|:           ||  ||.|:.....|.:.:..
Human    93 MLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAG--EGGGVIQGSASEATLVA 155

  Fly   168 MVLARYKI-------APEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGL-GSYNCVSVRTNER 224
            ::.||.|:       :||:..:.:  |..||.::||::|.|..:|    || |.....::.::..
Human   156 LLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERA----GLIGGVKLKAIPSDGN 214

  Fly   225 GQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAAL 289
            ..|....|:..:...||.|..|||:..|.|||...:||::.....:..:..:||||||...|:|.
Human   215 FAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAF 279

  Fly   290 LSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFY--D 352
            :..:.|.|:.|:|.|:||::||||.:.....||....:      :|.:.|.|   |:.|..|  .
Human   280 ICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVK------KRTDLTGA---FRLDPTYLKH 335

  Fly   353 VSYDTG------NKSVQCGRKIDAFKFWLMLKARGYGKYGLM--VDHAIHIARLLEGKLRQRGDR 409
            ...|:|      :..:..||:..:.|.|.:.  |.||..||.  :...:.::...|..:|| ..|
Human   336 SHQDSGLITDYRHWQIPLGRRFRSLKMWFVF--RMYGVKGLQAYIRKHVQLSHEFESLVRQ-DPR 397

  Fly   410 FRLVIPEHEYSNVCF 424
            |.:.: |.....|||
Human   398 FEICV-EVILGLVCF 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	92/362 (25%)
DDC	NP_000781.2	Pyridoxal_deC	35..414	CDD:365998	99/405 (24%)
		2 X approximate tandem repeats	58..178		24/142 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810