Protein Alignment CG5618 and Hdc

DIOPT Version :10

• Sequence 1: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_006498847.1
• Gene: Hdc / 15186
• MGIID: 96062
• Length: 681
• Species: Mus musculus
• Alignment Length: 383
• Identity: 94/383 - (24%)
• Similarity: 169/383 - (44%)
• Gaps: 41/383 - (10%)

  Fly    47 KQKIVPFLQPDKLKELINLKVRE---TENCSLAEIEELCQQ-VIHYSVKTSHGRFHNQLFGQLDP 107
            ::::.|.:||..|:..:.....|   :.:....:||.:... |:|:.....|.     .:..|..
Mouse    53 ERQVTPNVQPGYLRAQLPASAPEEPDSWDSIFGDIERVIMPGVVHWQSPHMHA-----YYPALTS 112

  Fly   108 F-GLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKE----------GDGIFAPGGS 161
            : .|.|.::.:|:|...:|:..:|..:.:|..::..:.|:.|..|          |.|:.....|
Mouse   113 WPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPEYFLHHHPSSRGGGVLQSTVS 177

  Fly   162 TSNMYGMVLAR-YKI------APEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSV 219
            .|.:..::.|| .||      .|:...|.:...  ||.:|||::|.|..||      |..:.|.:
Mouse   178 ESTLIALLAARKNKILAMKACEPDANESSLNAR--LVAYTSDQAHSSVEKA------GLISLVKI 234

  Fly   220 R---TNERGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVD 281
            |   .::...:..:.|:..|.|.|.:|..|.||..|.|||.:.|||.::....:....|||||||
Mouse   235 RFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDRLSELGPICASEGLWLHVD 299

  Fly   282 ACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQ 346
            |...|.|.|..:.|..:.|:|.|:||::||.|.:.....|:.|..::..: |::..|....||..
Mouse   300 AAYAGTAFLCPELRGFLEGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYK-LQQTFSVNPIYLRH 363

  Fly   347 QDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLR 404
            .:.  ..:.|..:..:...|:..:.|.|.::::.|.......|.|...:|:..|..:|
Mouse   364 ANS--GAATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5618	NP_649211.1	GadA	56..507	CDD:439846	92/374 (25%)
Hdc	XP_006498847.1	Pyridoxal_deC	62..440	CDD:395219	92/374 (25%)