DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5618 and gad2

DIOPT Version :9

Sequence 1:NP_649211.1 Gene:CG5618 / 40241 FlyBaseID:FBgn0036975 Length:510 Species:Drosophila melanogaster
Sequence 2:XP_017950266.1 Gene:gad2 / 100493806 XenbaseID:XB-GENE-976598 Length:588 Species:Xenopus tropicalis


Alignment Length:472 Identity:206/472 - (43%)
Similarity:305/472 - (64%) Gaps:16/472 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 QKWDKQ-KIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLD 106
            |.:|:. |::.|..|::|.:..|.::.|... ||..|...|:..:.|::||.|.|:.|||...||
 Frog   127 QTFDRSTKVIDFHYPNELLQAYNWELSEQPQ-SLDGILLNCKTTLKYAIKTGHPRYFNQLSTGLD 190

  Fly   107 PFGLAGALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYK--EGDGIFAPGGSTSNMYGMV 169
            ..|||...:|...|.:.:|||:||||.|:|...:..:.::.|:.  .|||||:|||:.||:|.|:
 Frog   191 MVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREMIGWPGGSGDGIFSPGGAISNLYAML 255

  Fly   170 LARYKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEA 234
            :||:|:.||||..||..:..||.|||:.||:|..|.|..||:|:.:.:.::.:|||:::..|||.
 Frog   256 IARFKMFPEVKEKGMAALPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIKADERGRLIPSDLER 320

  Fly   235 KIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNRSLIA 299
            :|.|||..|..||||:.||||||.||||.:...||:.:::.:|:||||..||..|:|.|::..:.
 Frog   321 RIIEAKQNGYVPFFVSATAGTTVYGAFDPLVSIADICKKYRIWMHVDAAWGGGLLMSRKHKWKLN 385

  Fly   300 GLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQC 364
            |.:||||.:|||||.:|.|||||..|.||.| |::.||...|.|||||||.||:|||||:|::||
 Frog   386 GADRANSVTWNPHKMMGVPLQCSALLVREEG-LMQNCNQMHASYLFQQDKHYDLSYDTGDKALQC 449

  Fly   365 GRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVI---PEHEYSNVCFWF 426
            ||.:|.||.|||.:|:|...:...:|..:.::..|..|::.| :.:.:||   |:|  :|||||:
 Frog   450 GRHVDIFKLWLMWRAKGTTGFEAHIDKCLELSEYLYNKIKNR-EGYEMVIEGKPQH--TNVCFWY 511

  Fly   427 IPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKS 491
            :|.::|  :.|:..|..:||..|||.||.:|...||.|:.|.|...|  |||||||.: .|....
 Frog   512 VPPSLR--NMEDNEERMNRLSKVAPIIKARMMEYGTTMVSYQPHGDK--GNFFRMVIS-NPAAAH 571

  Fly   492 KELDFILDEIERLGEKI 508
            :::||:::||||||:.:
 Frog   572 QDIDFLIEEIERLGQDL 588

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5618NP_649211.1 AAT_I 97..504 CDD:302748 186/411 (45%)
gad2XP_017950266.1 Pyridoxal_deC 141..512 CDD:365998 168/375 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D162307at33208
OrthoFinder 1 1.000 - - FOG0000667
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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